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grh | Protein grainyhead; Grainy head (grh) encodes the founding member of a highly conserved family of transcription factors essential for embryonic development. It is both a transcriptional activator and repressor, responsible for the proper expression of many genes primarily involved in epithelial cell fate, barrier formation, wound healing, tube morphogenesis and proliferation of larval neuroblasts; Belongs to the grh/CP2 family. Grainyhead subfamily. (1333 aa) | ||||
sisA | Sisterless A (sisA) encodes a transcription factor that activates transcription of the master feminizing switch gene Sxl specifically in diplo-X somatic cells. It is also required for proper embryonic midgut development in both sexes. (189 aa) |