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The following proteins in
Drosophila melanogaster
appear to match your input.
Please review the list, then click 'Continue' to proceed.
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1) '7227.FBpp0288984':
grh - Protein grainyhead; Grainy head (grh) encodes the founding member of a highly conserved family of transcription factors essential for embryonic development. It is both a transcriptional activator and repressor, responsible for the proper expression of many genes primarily involved in epithelial cell fate, barrier formation, wound healing, tube morphogenesis and proliferation of larval neuroblasts; Belongs to the grh/CP2 family. Grainyhead subfamily.
[a.k.a. FBgn0259211, grh-PJ, grh-PP,
7227.FBpp0288984
]
2) '7227.FBpp0304981':
fz2 - Frizzled-2; Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to i [...]
[a.k.a. FBgn0016797, fz2-PD, fz2-PF,
7227.FBpp0304981
]