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The following proteins in
Drosophila melanogaster
appear to match your input.
Please review the list, then click 'Continue' to proceed.
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⤓ Mapping
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1) '7227.FBpp0291454':
Set1 - Histone-lysine N-methyltransferase SETD1; Catalytic component of the SET1 complex that specifically di- and trimethylates 'Lys-4' of histone H3 and is the main di- and trimethyltransferase throughout development. Set1-dependent trimethylation regulates chromatin changes at active promoters that ensure optimal RNA polymerase II release into productive elongation, thereby contributing to optimal transcription.
[a.k.a. FBgn0040022, Set1-PA, Set1-PH,
7227.FBpp0291454
]
2) '7227.FBpp0082538':
ear - ENL/AF9-related, isoform B; ENL/AF9-related (ear) encodes a transcription factor that is a component of the super elongation complex (SEC), which regulates transcription by RNA Polymerase II. It also interacts with the histone methyltransferase encoded by gpp in the Dot1 complex (DotCom), which modifies chromatin structure by methylating histone H3 on lysine 79.
[a.k.a. FBgn0026441, ear-PA, ear-PC,
7227.FBpp0082538
]