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The following proteins in
Drosophila melanogaster
appear to match your input.
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⤓ Mapping
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1) '7227.FBpp0291454':
Set1 - Histone-lysine N-methyltransferase SETD1; Catalytic component of the SET1 complex that specifically di- and trimethylates 'Lys-4' of histone H3 and is the main di- and trimethyltransferase throughout development. Set1-dependent trimethylation regulates chromatin changes at active promoters that ensure optimal RNA polymerase II release into productive elongation, thereby contributing to optimal transcription.
[a.k.a. FBgn0040022, Set1-PA, Set1-PH,
7227.FBpp0291454
]
2) '7227.FBpp0086711':
Uba3 - Nedd8-activating enzyme E1 catalytic subunit; Catalytic subunit of the dimeric Uba3-APP-BP1 E1 enzyme. E1 activates Nedd8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a Nedd8-Uba3 thioester and free AMP. E1 finally transfers Nedd8 to the catalytic cysteine of UbcE2M. Required for Cul1 and Cul3 neddylation. Negatively regulates full-length ci stability and hedgehog signaling.
[a.k.a. FBgn0263697, Uba3-PA, Q4QPQ3,
7227.FBpp0086711
]