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The following proteins in
Drosophila melanogaster
appear to match your input.
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⤓ Mapping
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1) '7227.FBpp0291454':
Set1 - Histone-lysine N-methyltransferase SETD1; Catalytic component of the SET1 complex that specifically di- and trimethylates 'Lys-4' of histone H3 and is the main di- and trimethyltransferase throughout development. Set1-dependent trimethylation regulates chromatin changes at active promoters that ensure optimal RNA polymerase II release into productive elongation, thereby contributing to optimal transcription.
[a.k.a. FBgn0040022, Set1-PA, Set1-PH,
7227.FBpp0291454
]
2) 'DNApol-theta':
DNApol-theta
- DNA polymerase theta; Multifunctional protein with both DNA polymerase and ATPase activities. Might have 3' to 5' exonuclease activity. Plays a role in different DNA repair pathways such as DNA strand cross-link repair and microhomology- mediated end-joining (MMEJ), an alternative non-homologous end-joining (NHEJ) machinery triggered in response to double-strand breaks. MMEJ is an error- prone repair pathway that produces deletions of sequences from the strand being repaired and promotes genomic rearrangements, such as telomere fusions. Utilizes short microhomologies present in partial [...]