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Su(var)3-9 | Histone-lysine N-methyltransferase Su(var)3-9; Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3 using monomethylated H3 'Lys-9' as substrate. H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting Su(var)205/HP1 to methylated histones. Mainly functions in heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin at pericentric regions. Involved in heterochromatic gene silencing including the modification of position-effect-variegation. Belongs to the cl [...] (635 aa) | ||||
His4:CG33901 | His4:CG33901 (His4:CG33901) encodes a histone H4 replacement variant that is part of the nucleosome core. It is the predominant histone H4 in non-dividing cells. Its amino acid sequence is identical to the cell-cycle regulated histone encoded by His4. (103 aa) |