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Mad | Mothers against dpp (Mad) encodes the primary transcription factor that mediates cellular response to the BMP like ligands encoded by dpp, scw and gbb. Upon phosphorylation by either the products of sax or tkv (type I BMP receptors), it forms a complex with the product of Med and translocates to the nucleus where, together with cofactors, it regulates expression of BMP response target genes; Belongs to the dwarfin/SMAD family. (525 aa) | ||||
CG31674 | FI03731p; Glyoxylate reductase (NADP) activity; NAD binding; glycerate dehydrogenase activity; hydroxypyruvate reductase activity; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor. It is involved in the biological process described with: oxidation-reduction process; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (327 aa) |