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The following proteins in
Drosophila melanogaster
appear to match your input.
Please review the list, then click 'Continue' to proceed.
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⤓ Mapping
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1) '7227.FBpp0304648':
Mad - Mothers against dpp (Mad) encodes the primary transcription factor that mediates cellular response to the BMP like ligands encoded by dpp, scw and gbb. Upon phosphorylation by either the products of sax or tkv (type I BMP receptors), it forms a complex with the product of Med and translocates to the nucleus where, together with cofactors, it regulates expression of BMP response target genes; Belongs to the dwarfin/SMAD family.
[a.k.a. FBgn0011648, Mad-PB, Mad-PA,
7227.FBpp0304648
]
2) 'tal-2A':
tal-2A
- Tarsal-less
2A
(
tal
-
2A
) encodes one of four open reading frames within the
tal
polycistronic transcription unit. The encoded peptide controls the post-transcriptional activation of the product of ovo, which in turn regulates Notch signalling and F-actin organization.
tal-AA - Peptide tarsal-less AA; One of four peptides (
tal
-1A,
tal
-
2A
,
tal
-3A and
tal
-AA) produced from a polycistronic gene that function redundantly in several developmental processes. Required in early stages of leg development for the intercalation of the tarsal segments during the mid-third instar stage and later for tarsal joint formation. Promotes the post- translational modification of ovo isoform B (svb) into its active form which in turn initiates trichome development and promotes tarsal joint development. This is likely due to recruitment of the E3 ubiquitin-protein ligase Ubr3 to sv [...]
[a.k.a. FBgn0259733, tal-AA-PA, NP_001138049.1]