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Trl | Transcription factor GAGA; Transcriptional activator that functions by regulating chromatin structure. Overcomes the repressive effects of chromatin by promoting the open chromatin conformation in promoter gene regions, thereby allowing access to other transcription factors. Binds to DNA Polycomb response elements (PREs) at the bithorax complex and to the proximal region of the engrailed promoter, and positively regulates transcription of many genes including homeotic ones. Binds to the DNA sequence (GA)n, with optimal binding to the pentamer 5'-GAGAG-3'. Binds DNA as an oligomer. May [...] (623 aa) | ||||
CG1620 | Uncharacterized protein, isoform A; RNA polymerase II repressing transcription factor binding; histone deacetylase binding; transcription corepressor activity; DNA binding. It is involved in the biological process described with: histone deacetylation; negative regulation of transcription by RNA polymerase II. (586 aa) |