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Trl | Transcription factor GAGA; Transcriptional activator that functions by regulating chromatin structure. Overcomes the repressive effects of chromatin by promoting the open chromatin conformation in promoter gene regions, thereby allowing access to other transcription factors. Binds to DNA Polycomb response elements (PREs) at the bithorax complex and to the proximal region of the engrailed promoter, and positively regulates transcription of many genes including homeotic ones. Binds to the DNA sequence (GA)n, with optimal binding to the pentamer 5'-GAGAG-3'. Binds DNA as an oligomer. May [...] (623 aa) | ||||
Pex3 | Peroxin 3 (Pex3) encodes a peroxisomal membrane protein (PMP) involved in de novo peroxisome biogenesis from the endoplasmic reticulum and PMP import from the cytosol. It also facilitates the insertion of proteins into the membrane of mature peroxisomes via its interaction with the PMP chaperone encoded by Pex19. (385 aa) |