Your Input: | |||||
Gug | Grunge, isoform J; Grunge (Gug) encodes a nuclear repressor protein that likely responds to Egfr signaling to control cell behavior for normal developmental patterning. (2007 aa) | ||||
Saf6 | SAGA factor-like TAF6 (Saf6) encodes a component of the Spt-Ada-Gcn5 Acetyltransferase (SAGA) chromatin modifying complex. This complex is responsible for acetylation of histones and deubiquitination of the product of His2B at active promoters. The product of Saf6 replaces the product of mia within SAGA when the product of mia is restricted to the TFIID transcription complex. Notably, the product of Saf6 is essential for SAGA's co-activator function but does not impact either of its enzymatic activities. (717 aa) |