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HDAC4 | Histone deacetylase 4, isoform G; Histone deacetylase 4 (HDAC4) encodes a Class IIa histone deacetylase that modulates gene expression by associating with transcriptional factors. It is regulated by nucleocytoplasmic shuttling and contributes to embryogenesis, muscle development, circadian function, energy balance and memory. (1269 aa) | ||||
mTerf5 | Transcription termination factor 5, mitochondrial; Binds promoter DNA and regulates initiation of transcription. Regulates mitochondrial replication and transcription. Required for normal topology and maintenance of mitochondrial DNA (mtDNA) levels. Regulates mtDNA replication by re- activating replication after replication pausing. Likely to regulate replication pausing by coordinating with the mitochondrial termination factor mTTF which promotes replication pausing. Their function in replication pausing prevents unregulated replication that may occur for example by collisions between [...] (560 aa) |