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MRG15 | NuA4 complex subunit EAF3 homolog; Part of the Tip60 chromatin-remodeling complex which is involved in DNA repair. Upon induction of DNA double-strand breaks, this complex acetylates phosphorylated H2AV in nucleosomes and exchanges it with unmodified H2AV. (429 aa) | ||||
Cnb | Centrobin, isoform A; Centrobin (Cnb) encodes a protein that localizes to the daughter centriole. In neuroblasts, its centriolar localization results in peri-centriolar material retention during interphase. This function requires the phosphorilation of the product of Cnb by the kinase encoded by polo. In the neurons of type I sensory organs, the product of Cnb is necessary and sufficient to inhibit basal body function. (689 aa) |