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E(z) | Histone-lysine N-methyltransferase E(z); Polycomb group (PcG) protein. Catalytic subunit of the Esc/E(z) complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. While PcG proteins are generally required to maintain the transcriptionally repressive state of homeotic genes throughout development, this protein is specifically required during the first 6 hours of embryogenesis to establish the repressed state. The Esc/E(z) complex is necessary but not sufficient for the repression of homeotic target genes, suggesting [...] (765 aa) | ||||
l(3)psg2 | Lethal (3) persistent salivary gland 2; It is involved in the biological process described with: ecdysone-mediated induction of salivary gland cell autophagic cell death; imaginal disc-derived leg morphogenesis; regulation of programmed cell death. (1929 aa) |