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The following proteins in
Homo sapiens
appear to match your input.
Please review the list, then click 'Continue' to proceed.
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⤓ Mapping
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1) '9606.ENSP00000227163':
SPI1 - Transcription factor PU.1; Binds to the PU-box, a purine-rich DNA sequence (5'-GAGGAA- 3') that can act as a lymphoid-specific enhancer. This protein is a transcriptional activator that may be specifically involved in the differentiation or activation of macrophages or B-cells. Also binds RNA and may modulate pre-mRNA splicing (By similarity); Belongs to the ETS family.
[a.k.a. SPI-A, 6688, Transcription factor PU.1]
2) 'LOC102723996':
LOC102723996
- ICOS ligand; Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function (By similarity).
ICOSLG - Ig-like domain-containing protein; Inducible T cell costimulator ligand.
[a.k.a. NP_001269979, UPI00003E27DA, CH471079,
LOC102723996
]