Version:
12.0
Login
Register
Survey
STRING
STRING
Search
Download
Help
My Data
The following proteins in
Homo sapiens
appear to match your input.
Please review the list, then click 'Continue' to proceed.
<- Back
⤓ Mapping
Continue ->
1) '9606.ENSP00000228872':
CDKN1B - Cyclin-dependent kinase inhibitor 1B; Important regulator of cell cycle progression. Inhibits the kinase activity of CDK2 bound to cyclin A, but has little inhibitory activity on CDK2 bound to SPDYA. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1-CDK4 complex activation. Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry. Belongs to the CDI family.
[a.k.a. R-HSA-9006925, R-HSA-69278, R-HSA-69620]
2) 'NOTCH2NLB':
NOTCH2NLB
- Notch homolog 2 N-terminal-like protein B; Human-specific protein that promotes neural progenitor proliferation and evolutionary expansion of the brain neocortex by regulating the Notch signaling pathway. Able to promote neural progenitor self-renewal, possibly by down-regulating neuronal differentiation genes, thereby delaying the differentiation of neuronal progenitors and leading to an overall final increase in neuronal production. Acts by enhancing the Notch signaling pathway via two different mechanisms that probably work in parallel to reach the same effect. Enhances Notch signal [...]