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STRING
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The following proteins in
Homo sapiens
appear to match your input.
Please review the list, then click 'Continue' to proceed.
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⤓ Mapping
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1) '9606.ENSP00000249636':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
2) '9606.ENSP00000245787':
INSIG2 - Insulin-induced gene 2 protein; Mediates feedback control of cholesterol synthesis by controlling SCAP and HMGCR. Functions by blocking the processing of sterol regulatory element-binding proteins (SREBPs). Capable of retaining the SCAP-SREBF2 complex in the ER thus preventing it from escorting SREBPs to the Golgi. Seems to regulate the ubiquitin-mediated proteasomal degradation of HMGCR.
[a.k.a. INSIG2-203, AAN28333.1, Q9Y5U4]