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SOX17 | Transcription factor SOX-17; Acts as transcription regulator that binds target promoter DNA and bends the DNA. Binds to the sequences 5'-AACAAT-'3 or 5'- AACAAAG-3'. Modulates transcriptional regulation via WNT3A. Inhibits Wnt signaling. Promotes degradation of activated CTNNB1. Plays a key role in the regulation of embryonic development. Required for normal development of the definitive gut endoderm. Required for normal looping of the embryonic heart tube. Plays an important role in embryonic and postnatal vascular development, including development of arteries. Plays an important rol [...] (414 aa) | ||||
SBK2 | Serine/threonine-protein kinase SBK2; SH3 domain binding kinase family member 2; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. STKL subfamily. (348 aa) |