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The following proteins in
Homo sapiens
appear to match your input.
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⤓ Mapping
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1) '9606.ENSP00000345206':
RBPJ - Recombining binding protein suppressor of hairless; Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate determinations. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some NICD product of Notch proteins (Notch intracellular domain), it acts as a transcriptional activator that activates transcription of Notch target genes. Probably represses or activates transcription via the recruitment of chromatin remodeling [...]
[a.k.a. ENST00000510725.1, ENST00000511546.5, RBPJ-228]
2) 'NOTCH2NLC':
NOTCH2NLC
- Notch 2 N-terminal like C.
NOTCH2NLA - Notch homolog 2 N-terminal-like protein A; Human-specific protein that promotes neural progenitor proliferation and evolutionary expansion of the brain neocortex by regulating the Notch signaling pathway. Able to promote neural progenitor self-renewal, possibly by down-regulating neuronal differentiation genes, thereby delaying the differentiation of neuronal progenitors and leading to an overall final increase in neuronal production. Acts by enhancing the Notch signaling pathway via two different mechanisms that probably work in parallel to reach the same effect. Enhances Notch signal [...]
[a.k.a. P0DPK4, Q5XG84, uc031utx.2,
NOTCH2NLC
]