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SRPK1 | SRSF protein kinase 1; Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains and is involved in the phosphorylation of SR splicing factors and the regulation of splicing. Plays a central role in the regulatory network for splicing, controlling the intranuclear distribution of splicing factors in interphase cells and the reorganization of nuclear speckles during mitosis. Can influence additional steps of mRNA maturation, as well as other cellular activiti [...] (655 aa) | ||||
PRRG4 | Transmembrane gamma-carboxyglutamic acid protein 4; May control axon guidance across the CNS. Prevents the delivery of ROBO1 at the cell surface and downregulates its expression ; Belongs to the commissureless family. (226 aa) |