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PRPF4 | U4/U6 small nuclear ribonucleoprotein Prp4; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). (522 aa) | ||||
ALKBH2 | DNA oxidative demethylase ALKBH2; Dioxygenase that repairs alkylated DNA and RNA containing 1- methyladenine and 3-methylcytosine by oxidative demethylation. Can also repair alkylated DNA containing 1-ethenoadenine (in vitro). Has strong preference for double-stranded DNA. Has low efficiency with single- stranded substrates. Requires molecular oxygen, alpha-ketoglutarate and iron. (261 aa) |