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GATA1 | Erythroid transcription factor; Transcriptional activator or repressor which probably serves as a general switch factor for erythroid development. It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of globin genes and of other genes expressed in erythroid cells. Activates the transcription of genes involved in erythroid differentiation of K562 erythroleukemia cells, including HBB, HBG1/2, ALAS2 and HMBS. (413 aa) | ||||
SLFN14 | C-terminally truncated SLFN14 endoribonuclease; [Protein SLFN14]: Shows no ribosome-associated and endoribonuclease activities; Belongs to the Schlafen family. Subgroup III subfamily. (912 aa) |