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STRING
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The following proteins in
Homo sapiens
appear to match your input.
Please review the list, then click 'Continue' to proceed.
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⤓ Mapping
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1) '9606.ENSP00000368924':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
2) '9606.ENSP00000316845':
ARHGEF4 - Rho guanine nucleotide exchange factor 4; Acts as guanine nucleotide exchange factor (GEF) for RHOA, RAC1 and CDC42 GTPases. Binding of APC may activate RAC1 GEF activity. The APC-ARHGEF4 complex seems to be involved in cell migration as well as in E-cadherin-mediated cell-cell adhesion. Required for MMP9 up- regulation via the JNK signaling pathway in colorectal tumor cells. Involved in tumor angiogenesis and may play a role in intestinal adenoma formation and tumor progression.
[a.k.a. R-HSA-388396, XP_011509576, Rho guanine nucleotide exchange factor (GEF) 4]