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The following proteins in
Homo sapiens
appear to match your input.
Please review the list, then click 'Continue' to proceed.
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⤓ Mapping
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1) '9606.ENSP00000380034':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
2) '9606.ENSP00000326366':
PSEN1 - Presenilin-1 CTF subunit; Catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid- beta precursor protein). Requires the presence of the other members of the gamma-secretase complex for protease activity. Plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins, and by regulating cytosolic CTNNB1 levels. Stimulates cell-cell adhesion via its interaction with CDH1; this stabili [...]
[a.k.a. ENST00000555254.5, ENST00000557356.5, UPI000013D235]