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PRAME | Melanoma antigen preferentially expressed in tumors; Functions as a transcriptional repressor, inhibiting the signaling of retinoic acid through the retinoic acid receptors RARA, RARB and RARG. Prevents retinoic acid-induced cell proliferation arrest, differentiation and apoptosis. (509 aa) | ||||
SCAF11 | Protein SCAF11; Plays a role in pre-mRNA alternative splicing by regulating spliceosome assembly. (1463 aa) |