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C17orf49 | Chromatin complexes subunit BAP18; Component of chromatin complexes such as the MLL1/MLL and NURF complexes. (192 aa) | ||||
FBXO31 | F-box only protein 31; Component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in G1 arrest following DNA damage. Specifically recognizes phosphorylated cyclin-D1 (CCND1), promoting its ubiquitination and degradation by the proteasome, resulting in G1 arrest. May act as a tumor suppressor; Belongs to the FBXO31 family. (539 aa) |