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The following proteins in
Homo sapiens
appear to match your input.
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⤓ Mapping
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1) 'PEX6':
PEX6
- Peroxisome assembly factor 2; Involved in peroxisome biosynthesis. Required for stability of the PTS1 receptor. Anchored by PEX26 to peroxisome membranes, possibly to form heteromeric AAA ATPase complexes required for the import of proteins into peroxisomes.
PEX26 - Peroxisome assembly protein 26; Probably required for protein import into peroxisomes. Anchors PEX1 and
PEX6
to peroxisome membranes, possibly to form heteromeric AAA ATPase complexes required for the import of proteins into peroxisomes. Involved in the import of catalase and proteins containing a PTS2 target sequence, but not in import of proteins with a PTS1 target sequence.
[a.k.a. EAW57782.1, ENSP00000434235, ENSP00000482091]
ZFAND6 - AN1-type zinc finger protein 6; Involved in regulation of TNF-alpha induced NF-kappa-B activation and apoptosis. Involved in modulation of 'Lys-48'-linked polyubiquitination status of TRAF2 and decreases association of TRAF2 with RIPK1. Required for PTS1 target sequence-dependent protein import into peroxisomes and PEX5 stability; may cooperate with
PEX6
. In vitro involved in PEX5 export from the cytosol to peroxisomes (By similarity).
[a.k.a. NP_001229843.1, XM_011521684.2, ENST00000613266]
2) 'OCA2':
OCA2
- P protein; Could be involved in the transport of tyrosine, the precursor to melanin synthesis, within the melanocyte. Regulates the pH of melanosome and the melanosome maturation. One of the components of the mammalian pigmentary system. Seems to regulate the post-translational processing of tyrosinase, which catalyzes the limiting reaction in melanin synthesis. May serve as a key control point at which ethnic skin color variation is determined. Major determinant of brown and/or blue eye color. Belongs to the CitM (TC 2.A.11) transporter family.