Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small nodes:
protein of unknown 3D structure
protein of unknown 3D structure
large nodes:
some 3D structure is known or predicted
some 3D structure is known or predicted
Node Color
colored nodes:
query proteins and first shell of interactors
query proteins and first shell of interactors
white nodes:
second shell of interactors
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Your Input:
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Neighborhood |
Gene Fusion |
Cooccurence |
Coexpression |
Experiments |
Databases |
Textmining |
[Homology] |
Score |
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 | LmjF.20.1185 | cysteine peptidase, Clan CA, family C2, putative.[Source-GeneDB;Acc-LmjF.20.1185] (823 aa) | ||||||||||||
Predicted Functional Partners:
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 | LmjF.27.1640 | hypothetical protein, conserved.[Source-GeneDB;Acc-LmjF.27.1640] (914 aa) |
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0.741 | |||||||||
 | MCA5 | metacaspase, putative.[Source-GeneDB;Acc-LmjF.35.1580] (435 aa) |
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0.665 | ||||||||||
 | LmjF.20.1680 | separin, putative.[Source-GeneDB;Acc-LmjF.20.1680] (1279 aa) |
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0.644 | ||||||||||
 | LmjF.35.4400 | hypothetical protein, conserved.[Source-GeneDB;Acc-LmjF.35.4400] (206 aa) |
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0.630 | ||||||||||
 | LmjF.33.1900 | vesicular protein trafficking mediator, putative.[Source-GeneDB;Acc-LmjF.33.1900] (204 aa) |
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0.630 | ||||||||||
 | LmjF.35.4850 | proteasome alpha 1 subunit, putative.[Source-GeneDB;Acc-LmjF.35.4850]; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity (By similarity) (250 aa) |
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0.618 | ||||||||||
 | LmjF.28.0110 | proteasome beta 3 subunit, putative.[Source-GeneDB;Acc-LmjF.28.0110]; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity (By similarity) (205 aa) |
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0.606 | ||||||||||
 | LmjF.35.2080 | calcium motive p-type ATPase, putative.[Source-GeneDB;Acc-LmjF.35.2080] (1109 aa) |
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0.556 | ||||||||||
 | L2385.06 | proton motive ATPase, putative.[Source-GeneDB;Acc-LmjF.04.1110] (952 aa) |
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0.556 | ||||||||||
 | LT.01 | calcium-translocating P-type ATPase.[Source-GeneDB;Acc-LmjF.04.0010] (1023 aa) |
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0.556 | ||||||||||
Your Current Organism:
Leishmania major
NCBI taxonomy Id: 5664
Other names: L. major, L. major species complex, Leishmania (Leishmania) major, Leishmania major, Leishmania major species complex, Leishmania tropica major
Other names: L. major, L. major species complex, Leishmania (Leishmania) major, Leishmania major, Leishmania major species complex, Leishmania tropica major
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