Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small nodes:
protein of unknown 3D structure
protein of unknown 3D structure
large nodes:
some 3D structure is known or predicted
some 3D structure is known or predicted
Node Color
colored nodes:
query proteins and first shell of interactors
query proteins and first shell of interactors
white nodes:
second shell of interactors
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Your Input:
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Neighborhood |
Gene Fusion |
Cooccurence |
Coexpression |
Experiments |
Databases |
Textmining |
[Homology] |
Score |
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 | LmjF.25.0190 | cysteine peptidase, Clan CA, family C12, putative.[Source-GeneDB;Acc-LmjF.25.0190] (233 aa) | ||||||||||||
Predicted Functional Partners:
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 | LmjF.31.2030 | ubiquitin-fusion protein.[Source-GeneDB;Acc-LmjF.31.2030]; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked- Lys [...] (128 aa) |
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0.993 | ||||||||
 | UB-EP52 | ubiquitin-fusion protein.[Source-GeneDB;Acc-LmjF.31.1900]; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked- Lys [...] (128 aa) |
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0.993 | ||||||||
 | LmjF.16.0850 | metallo-peptidase, Clan MP, Family M67.[Source-GeneDB;Acc-LmjF.16.0850] (478 aa) |
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0.989 | ||||||||
 | LmjF.34.2125 | ubiquitin-like protein.[Source-GeneDB;Acc-LmjF.34.2125] (80 aa) |
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0.974 | ||||||||
 | LmjF.36.3530 | polyubiquitin, putative.[Source-GeneDB;Acc-LmjF.36.3530] (837 aa) |
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0.970 | |||||||||
 | LmjF.35.2410 | cysteine peptidase, Clan CA, family C19, putative.[Source-GeneDB;Acc-LmjF.35.2410] (923 aa) |
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0.768 | |||||||||
 | LmjF.27.1270 | cysteine peptidase, Clan CA, family C19, putative.[Source-GeneDB;Acc-LmjF.27.1270] (575 aa) |
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0.768 | |||||||||
 | LmjF.35.3060 | ubiquitin-activating enzyme e1, putative.[Source-GeneDB;Acc-LmjF.35.3060] (1154 aa) |
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0.748 | |||||||||
 | L6586.08 | ubiquitin-activating enzyme e1, putative.[Source-GeneDB;Acc-LmjF.23.0550] (1044 aa) |
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0.748 | |||||||||
 | LmjF.29.2300 | cysteine peptidase, Clan CA, family C19, putative.[Source-GeneDB;Acc-LmjF.29.2300] (748 aa) |
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0.744 | |||||||||
Your Current Organism:
Leishmania major
NCBI taxonomy Id: 5664
Other names: L. major, L. major species complex, Leishmania (Leishmania) major, Leishmania major, Leishmania major species complex, Leishmania tropica major
Other names: L. major, L. major species complex, Leishmania (Leishmania) major, Leishmania major, Leishmania major species complex, Leishmania tropica major
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