Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small nodes:
protein of unknown 3D structure
protein of unknown 3D structure
large nodes:
some 3D structure is known or predicted
some 3D structure is known or predicted
Node Color
colored nodes:
query proteins and first shell of interactors
query proteins and first shell of interactors
white nodes:
second shell of interactors
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Your Input:
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Neighborhood |
Gene Fusion |
Cooccurence |
Coexpression |
Experiments |
Databases |
Textmining |
[Homology] |
Score |
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 | AMA1 | Apical membrane antigen 1, AMA1; Involved in parasite invasion of erythrocytes (622 aa) | ||||||||||||
Predicted Functional Partners:
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 | PfRON2 | Rhoptry neck protein 2 (2189 aa) |
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0.999 | ||||||||
 | eba-175 | Erythrocyte binding antigen 175 (1502 aa) |
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0.993 | |||||||||
 | MSP1 | Merozoite surface protein 1 (1720 aa) |
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0.993 | |||||||||
 | PF10_0344 | Glutamate-rich protein (1233 aa) |
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0.990 | |||||||||
 | MAL8P1.73 | Putative uncharacterized protein (1156 aa) |
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0.982 | |||||||||
 | SPAM | Antigen (354 aa) |
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0.975 | |||||||||
 | eba-181 | Erythrocyte binding antigen-181 (1567 aa) |
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0.971 | |||||||||
 | PfRh5 | Reticulocyte-binding protein homologue 5 (526 aa) |
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0.964 | |||||||||
 | PF10_0352 | Merozoite surface protein (405 aa) |
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0.959 | |||||||||
 | PFL2460w | Coronin (602 aa) |
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0.957 | ||||||||||
Your Current Organism:
Plasmodium falciparum
NCBI taxonomy Id: 5833
Other names: Laverania, P. (Laverania), P. falciparum, Plasmodium (Laverania), Plasmodium (Laverania) falciparum, Plasmodium falciparum, malaria parasite P. falciparum
Other names: Laverania, P. (Laverania), P. falciparum, Plasmodium (Laverania), Plasmodium (Laverania) falciparum, Plasmodium falciparum, malaria parasite P. falciparum
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