| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| FEN-1 | MAL8P1.76 | PFD0420c | MAL8P1.76 | Flap endonuclease 1; Structure-specific nuclease with 5’-flap endonuclease and 5’-3’ exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5’-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5’-end of a downstream Okazaki fragment. It enters the flap from the 5’-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a [...] | Meiotic recombination protein dmc1-like protein | 0.579 |
| FEN-1 | PF08_0126 | PFD0420c | PF08_0126 | Flap endonuclease 1; Structure-specific nuclease with 5’-flap endonuclease and 5’-3’ exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5’-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5’-end of a downstream Okazaki fragment. It enters the flap from the 5’-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a [...] | DNA repair protein rad54, putative | 0.807 |
| FEN-1 | PF10_0080 | PFD0420c | PF10_0080 | Flap endonuclease 1; Structure-specific nuclease with 5’-flap endonuclease and 5’-3’ exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5’-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5’-end of a downstream Okazaki fragment. It enters the flap from the 5’-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a [...] | Endonuclease, putative | 0.495 |
| FEN-1 | PF10_0362 | PFD0420c | PF10_0362 | Flap endonuclease 1; Structure-specific nuclease with 5’-flap endonuclease and 5’-3’ exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5’-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5’-end of a downstream Okazaki fragment. It enters the flap from the 5’-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a [...] | DNA polymerase | 0.668 |
| FEN-1 | PF14_0278 | PFD0420c | PF14_0278 | Flap endonuclease 1; Structure-specific nuclease with 5’-flap endonuclease and 5’-3’ exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5’-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5’-end of a downstream Okazaki fragment. It enters the flap from the 5’-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a [...] | ATP-dependent DNA helicase, putative | 0.917 |
| FEN-1 | PFA0390w | PFD0420c | PFA0390w | Flap endonuclease 1; Structure-specific nuclease with 5’-flap endonuclease and 5’-3’ exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5’-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5’-end of a downstream Okazaki fragment. It enters the flap from the 5’-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a [...] | annotation not available | 0.950 |
| FEN-1 | PFD0935c | PFD0420c | PFD0935c | Flap endonuclease 1; Structure-specific nuclease with 5’-flap endonuclease and 5’-3’ exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5’-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5’-end of a downstream Okazaki fragment. It enters the flap from the 5’-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a [...] | Putative uncharacterized protein | 0.943 |
| FEN-1 | PFF0285c | PFD0420c | PFF0285c | Flap endonuclease 1; Structure-specific nuclease with 5’-flap endonuclease and 5’-3’ exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5’-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5’-end of a downstream Okazaki fragment. It enters the flap from the 5’-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a [...] | Probable DNA repair protein RAD50; Essential component of the MRN complex, a complex that possesses single-stranded DNA endonuclease and 3’ to 5’ exonuclease activities, and plays a central role in double-strand break (DSB) repair, chromosome morphogenesis, DNA repair and meiosis. In the complex, it mediates the ATP-binding and is probably required to bind DNA ends and hold them in close proximity (By similarity) | 0.928 |
| FEN-1 | PFI0910w | PFD0420c | PFI0910w | Flap endonuclease 1; Structure-specific nuclease with 5’-flap endonuclease and 5’-3’ exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5’-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5’-end of a downstream Okazaki fragment. It enters the flap from the 5’-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a [...] | DNA helicase, putative | 0.932 |
| FEN-1 | Rad51 | PFD0420c | PF11_0087 | Flap endonuclease 1; Structure-specific nuclease with 5’-flap endonuclease and 5’-3’ exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5’-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5’-end of a downstream Okazaki fragment. It enters the flap from the 5’-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a [...] | Recombinase Rad51 | 0.942 |
| MAL8P1.76 | FEN-1 | MAL8P1.76 | PFD0420c | Meiotic recombination protein dmc1-like protein | Flap endonuclease 1; Structure-specific nuclease with 5’-flap endonuclease and 5’-3’ exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5’-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5’-end of a downstream Okazaki fragment. It enters the flap from the 5’-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a [...] | 0.579 |
| MAL8P1.76 | PF08_0126 | MAL8P1.76 | PF08_0126 | Meiotic recombination protein dmc1-like protein | DNA repair protein rad54, putative | 0.978 |
| MAL8P1.76 | PF10_0080 | MAL8P1.76 | PF10_0080 | Meiotic recombination protein dmc1-like protein | Endonuclease, putative | 0.640 |
| MAL8P1.76 | PF10_0362 | MAL8P1.76 | PF10_0362 | Meiotic recombination protein dmc1-like protein | DNA polymerase | 0.430 |
| MAL8P1.76 | PF14_0278 | MAL8P1.76 | PF14_0278 | Meiotic recombination protein dmc1-like protein | ATP-dependent DNA helicase, putative | 0.646 |
| MAL8P1.76 | PFA0390w | MAL8P1.76 | PFA0390w | Meiotic recombination protein dmc1-like protein | annotation not available | 0.924 |
| MAL8P1.76 | PFD0935c | MAL8P1.76 | PFD0935c | Meiotic recombination protein dmc1-like protein | Putative uncharacterized protein | 0.997 |
| MAL8P1.76 | PFF0285c | MAL8P1.76 | PFF0285c | Meiotic recombination protein dmc1-like protein | Probable DNA repair protein RAD50; Essential component of the MRN complex, a complex that possesses single-stranded DNA endonuclease and 3’ to 5’ exonuclease activities, and plays a central role in double-strand break (DSB) repair, chromosome morphogenesis, DNA repair and meiosis. In the complex, it mediates the ATP-binding and is probably required to bind DNA ends and hold them in close proximity (By similarity) | 0.873 |
| MAL8P1.76 | PFI0910w | MAL8P1.76 | PFI0910w | Meiotic recombination protein dmc1-like protein | DNA helicase, putative | 0.646 |
| MAL8P1.76 | Rad51 | MAL8P1.76 | PF11_0087 | Meiotic recombination protein dmc1-like protein | Recombinase Rad51 | 0.975 |
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