PfPAP protein (Plasmodium falciparum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Size

small nodes:
protein of unknown 3D structure

large nodes:
some 3D structure is known or predicted

Node Color

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

PfPAP

Phosphatidic acid phosphatase (439 aa)

Predicted Functional Partners:

PFI0785c

0.698

PF08_0108

0.696

PFI0410c

0.661

PFC0185w

0.646

PF10_0138

0.643

PFL2460w

0.612

PfSUB1

0.609

PF11_0277

0.609

PFB0275w

0.607

PFE0175c

0.603

Your Current Organism:

Plasmodium falciparum

NCBI taxonomy Id: 5833
Other names: Laverania, P. (Laverania), P. falciparum, Plasmodium (Laverania), Plasmodium (Laverania) falciparum, Plasmodium falciparum, malaria parasite P. falciparum

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TSV: tab separated values - can be opened in Excel

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structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PF08_0108	PF10_0138	PF08_0108	PF10_0138	Plasmepsin 10	Conserved Plasmodium protein	0.971
PF08_0108	PF11_0277	PF08_0108	PF11_0277	Plasmepsin 10	Conserved Plasmodium protein	0.920
PF08_0108	PFB0275w	PF08_0108	PFB0275w	Plasmepsin 10	Metabolite/drug transporter, putative	0.965
PF08_0108	PFC0185w	PF08_0108	PFC0185w	Plasmepsin 10	Membrane skeletal protein IMC1-related	0.863
PF08_0108	PFE0175c	PF08_0108	PFE0175c	Plasmepsin 10	Unconventional myosin pfm-b	0.932
PF08_0108	PFI0410c	PF08_0108	PFI0410c	Plasmepsin 10	Putative uncharacterized protein	0.845
PF08_0108	PFI0785c	PF08_0108	PFI0785c	Plasmepsin 10	Sugar transporter, putative	0.748
PF08_0108	PFL2460w	PF08_0108	PFL2460w	Plasmepsin 10	Coronin	0.976
PF08_0108	PfPAP	PF08_0108	PFF1210w	Plasmepsin 10	Phosphatidic acid phosphatase	0.696
PF08_0108	PfSUB1	PF08_0108	PFE0370c	Plasmepsin 10	Subtilisin-like protease 1	0.936
PF10_0138	PF08_0108	PF10_0138	PF08_0108	Conserved Plasmodium protein	Plasmepsin 10	0.971
PF10_0138	PF11_0277	PF10_0138	PF11_0277	Conserved Plasmodium protein	Conserved Plasmodium protein	0.927
PF10_0138	PFB0275w	PF10_0138	PFB0275w	Conserved Plasmodium protein	Metabolite/drug transporter, putative	0.895
PF10_0138	PFC0185w	PF10_0138	PFC0185w	Conserved Plasmodium protein	Membrane skeletal protein IMC1-related	0.906
PF10_0138	PFE0175c	PF10_0138	PFE0175c	Conserved Plasmodium protein	Unconventional myosin pfm-b	0.916
PF10_0138	PFI0410c	PF10_0138	PFI0410c	Conserved Plasmodium protein	Putative uncharacterized protein	0.889
PF10_0138	PFI0785c	PF10_0138	PFI0785c	Conserved Plasmodium protein	Sugar transporter, putative	0.826
PF10_0138	PFL2460w	PF10_0138	PFL2460w	Conserved Plasmodium protein	Coronin	0.964
PF10_0138	PfPAP	PF10_0138	PFF1210w	Conserved Plasmodium protein	Phosphatidic acid phosphatase	0.643
PF10_0138	PfSUB1	PF10_0138	PFE0370c	Conserved Plasmodium protein	Subtilisin-like protease 1	0.927

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