PGK protein (Plasmodium falciparum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Size

small nodes:
protein of unknown 3D structure

large nodes:
some 3D structure is known or predicted

Node Color

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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[Homology]

Score

PGK

Phosphoglycerate kinase (416 aa)

Predicted Functional Partners:

PF14_0378

0.999

GAPDH

0.999

PF10_0155

0.999

PF11_0208

0.999

PFC0831w

0.999

PF14_0341

0.993

PFF1300w

0.984

PF14_0425

0.972

pUB

0.966

PFI0755c

0.962

Your Current Organism:

Plasmodium falciparum

NCBI taxonomy Id: 5833
Other names: Laverania, P. (Laverania), P. falciparum, Plasmodium (Laverania), Plasmodium (Laverania) falciparum, Plasmodium falciparum, malaria parasite P. falciparum

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TSV: tab separated values - can be opened in Excel

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GAPDH	PF10_0155	PF14_0598	PF10_0155	Glyceraldehyde-3-phosphate dehydrogenase	Enolase	0.998
GAPDH	PF11_0208	PF14_0598	PF11_0208	Glyceraldehyde-3-phosphate dehydrogenase	Phosphoglycerate mutase	0.971
GAPDH	PF14_0341	PF14_0598	PF14_0341	Glyceraldehyde-3-phosphate dehydrogenase	Glucose-6-phosphate isomerase	0.985
GAPDH	PF14_0378	PF14_0598	PF14_0378	Glyceraldehyde-3-phosphate dehydrogenase	Triosephosphate isomerase	0.999
GAPDH	PF14_0425	PF14_0598	PF14_0425	Glyceraldehyde-3-phosphate dehydrogenase	Fructose-bisphosphate aldolase	0.997
GAPDH	PFC0831w	PF14_0598	PFC0831w	Glyceraldehyde-3-phosphate dehydrogenase	Triosephophate isomerase, putative	0.999
GAPDH	PFF1300w	PF14_0598	PFF1300w	Glyceraldehyde-3-phosphate dehydrogenase	Pyruvate kinase	0.920
GAPDH	PFI0755c	PF14_0598	PFI0755c	Glyceraldehyde-3-phosphate dehydrogenase	6-phosphofructokinase, putative	0.938
GAPDH	PGK	PF14_0598	PFI1105w	Glyceraldehyde-3-phosphate dehydrogenase	Phosphoglycerate kinase	0.999
GAPDH	pUB	PF14_0598	PFL0585w	Glyceraldehyde-3-phosphate dehydrogenase	Polyubiquitin	0.819
PF10_0155	GAPDH	PF10_0155	PF14_0598	Enolase	Glyceraldehyde-3-phosphate dehydrogenase	0.998
PF10_0155	PF11_0208	PF10_0155	PF11_0208	Enolase	Phosphoglycerate mutase	0.999
PF10_0155	PF14_0341	PF10_0155	PF14_0341	Enolase	Glucose-6-phosphate isomerase	0.996
PF10_0155	PF14_0378	PF10_0155	PF14_0378	Enolase	Triosephosphate isomerase	0.999
PF10_0155	PF14_0425	PF10_0155	PF14_0425	Enolase	Fructose-bisphosphate aldolase	0.971
PF10_0155	PFC0831w	PF10_0155	PFC0831w	Enolase	Triosephophate isomerase, putative	0.989
PF10_0155	PFF1300w	PF10_0155	PFF1300w	Enolase	Pyruvate kinase	0.999
PF10_0155	PFI0755c	PF10_0155	PFI0755c	Enolase	6-phosphofructokinase, putative	0.987
PF10_0155	PGK	PF10_0155	PFI1105w	Enolase	Phosphoglycerate kinase	0.999
PF10_0155	pUB	PF10_0155	PFL0585w	Enolase	Polyubiquitin	0.808

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