Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small nodes:
protein of unknown 3D structure
protein of unknown 3D structure
large nodes:
some 3D structure is known or predicted
some 3D structure is known or predicted
Node Color
colored nodes:
query proteins and first shell of interactors
query proteins and first shell of interactors
white nodes:
second shell of interactors
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Your Input:
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Neighborhood |
Gene Fusion |
Cooccurence |
Coexpression |
Experiments |
Databases |
Textmining |
[Homology] |
Score |
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 | PKH_020900 | Putative uncharacterized protein (2639 aa) | ||||||||||||
Predicted Functional Partners:
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 | PKH_142130 | Histone H2B ; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity) (123 aa) |
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0.456 | |||||||||
 | PKH_090230 | Histone H2B ; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity) (117 aa) |
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0.456 | |||||||||
 | PKH_114650 | Putative uncharacterized protein (915 aa) |
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0.433 | |||||||||
 | PKH_125830 | Putative uncharacterized protein (1237 aa) |
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0.412 | |||||||||
 | PKH_100480 | Ubiquitin carboxyl-terminal hydrolase (612 aa) |
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0.404 | |||||||||
Your Current Organism:
Plasmodium knowlesi
NCBI taxonomy Id: 5850
Other names: P. knowlesi, Plasmodium knowlesi
Other names: P. knowlesi, Plasmodium knowlesi
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