| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SPBC2D10.07c.1 | SPBC336.13c.1 | SPBC2D10.07c.1 | SPBC336.13c.1 | mitochondrial inner membrane peptidase complex catalytic subunit (predicted); Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space (By similarity) | mitochondrial inner membrane peptidase complex catalytic subunit 2 (predicted); Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space (By similarity) | 0.970 |
| SPBC2D10.07c.1 | sec11 | SPBC2D10.07c.1 | SPBC1685.03.1 | mitochondrial inner membrane peptidase complex catalytic subunit (predicted); Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space (By similarity) | signal peptidase subunit Sec11 (predicted); Catalytic component of the signal peptidase complex (SPC), which catalyzes the cleavage of N-terminal signal sequences of proteins targeted to the endoplasmic reticulum. Signal peptide cleavage occurs during the translocation (cotranslationally or post-translationally) through the translocon pore into the endoplasmic reticulum (By similarity) | 0.572 |
| SPBC2D10.07c.1 | spc2 | SPBC2D10.07c.1 | SPAC1071.04c.1 | mitochondrial inner membrane peptidase complex catalytic subunit (predicted); Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space (By similarity) | signal peptidase subunit Spc2 (predicted); Nonessential component of the signal peptidase complex (SPC), which catalyzes the cleavage of N-terminal signal sequences of proteins targeted to the endoplasmic reticulum. Signal peptide cleavage occurs during the translocation (cotranslationally or post-translationally) through the translocon pore into the endoplasmic reticulum. Spc2 enhances the enzymatic activity of SPC and facilitates the interactions between different components of the translocation site (By similarity) | 0.479 |
| SPBC2D10.07c.1 | spc3 | SPBC2D10.07c.1 | SPAC56F8.11.1 | mitochondrial inner membrane peptidase complex catalytic subunit (predicted); Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space (By similarity) | signal peptidase subunit Spc3 (predicted); Microsomal signal peptidase is a membrane-bound endoproteinase that removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity) | 0.574 |
| SPBC336.13c.1 | SPBC2D10.07c.1 | SPBC336.13c.1 | SPBC2D10.07c.1 | mitochondrial inner membrane peptidase complex catalytic subunit 2 (predicted); Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space (By similarity) | mitochondrial inner membrane peptidase complex catalytic subunit (predicted); Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space (By similarity) | 0.970 |
| SPBC336.13c.1 | spc2 | SPBC336.13c.1 | SPAC1071.04c.1 | mitochondrial inner membrane peptidase complex catalytic subunit 2 (predicted); Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space (By similarity) | signal peptidase subunit Spc2 (predicted); Nonessential component of the signal peptidase complex (SPC), which catalyzes the cleavage of N-terminal signal sequences of proteins targeted to the endoplasmic reticulum. Signal peptide cleavage occurs during the translocation (cotranslationally or post-translationally) through the translocon pore into the endoplasmic reticulum. Spc2 enhances the enzymatic activity of SPC and facilitates the interactions between different components of the translocation site (By similarity) | 0.479 |
| SPBC336.13c.1 | spc3 | SPBC336.13c.1 | SPAC56F8.11.1 | mitochondrial inner membrane peptidase complex catalytic subunit 2 (predicted); Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space (By similarity) | signal peptidase subunit Spc3 (predicted); Microsomal signal peptidase is a membrane-bound endoproteinase that removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity) | 0.574 |
| SPCC1281.06c.1 | erv25 | SPCC1281.06c.1 | SPAC23H4.03c.1 | acyl-coA desaturase (predicted); Utilizes O(2) and electrons from the reduced cytochrome b(5) domain to catalyze the insertion of a double bond into a spectrum of fatty acyl-CoA substrates (By similarity) | COPII-coated vesicle component Erv25 (predicted); Constituent of COPII-coated endoplasmic reticulum- derived transport vesicles. Required for efficient transport of a subset of secretory proteins to the Golgi. Facilitates retrograde transport from the Golgi to the endoplasmic reticulum (By similarity) | 0.744 |
| SPCC1281.06c.1 | sec11 | SPCC1281.06c.1 | SPBC1685.03.1 | acyl-coA desaturase (predicted); Utilizes O(2) and electrons from the reduced cytochrome b(5) domain to catalyze the insertion of a double bond into a spectrum of fatty acyl-CoA substrates (By similarity) | signal peptidase subunit Sec11 (predicted); Catalytic component of the signal peptidase complex (SPC), which catalyzes the cleavage of N-terminal signal sequences of proteins targeted to the endoplasmic reticulum. Signal peptide cleavage occurs during the translocation (cotranslationally or post-translationally) through the translocon pore into the endoplasmic reticulum (By similarity) | 0.773 |
| SPCC1281.06c.1 | spc2 | SPCC1281.06c.1 | SPAC1071.04c.1 | acyl-coA desaturase (predicted); Utilizes O(2) and electrons from the reduced cytochrome b(5) domain to catalyze the insertion of a double bond into a spectrum of fatty acyl-CoA substrates (By similarity) | signal peptidase subunit Spc2 (predicted); Nonessential component of the signal peptidase complex (SPC), which catalyzes the cleavage of N-terminal signal sequences of proteins targeted to the endoplasmic reticulum. Signal peptide cleavage occurs during the translocation (cotranslationally or post-translationally) through the translocon pore into the endoplasmic reticulum. Spc2 enhances the enzymatic activity of SPC and facilitates the interactions between different components of the translocation site (By similarity) | 0.856 |
| SPCC1281.06c.1 | spc3 | SPCC1281.06c.1 | SPAC56F8.11.1 | acyl-coA desaturase (predicted); Utilizes O(2) and electrons from the reduced cytochrome b(5) domain to catalyze the insertion of a double bond into a spectrum of fatty acyl-CoA substrates (By similarity) | signal peptidase subunit Spc3 (predicted); Microsomal signal peptidase is a membrane-bound endoproteinase that removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity) | 0.886 |
| clp1 | spc2 | SPAC1782.09c.1 | SPAC1071.04c.1 | Cdc14-related protein phosphatase Clp1/Flp1; Has a role in regulating entry into mitosis and promotes septum signaling | signal peptidase subunit Spc2 (predicted); Nonessential component of the signal peptidase complex (SPC), which catalyzes the cleavage of N-terminal signal sequences of proteins targeted to the endoplasmic reticulum. Signal peptide cleavage occurs during the translocation (cotranslationally or post-translationally) through the translocon pore into the endoplasmic reticulum. Spc2 enhances the enzymatic activity of SPC and facilitates the interactions between different components of the translocation site (By similarity) | 0.442 |
| erv25 | SPCC1281.06c.1 | SPAC23H4.03c.1 | SPCC1281.06c.1 | COPII-coated vesicle component Erv25 (predicted); Constituent of COPII-coated endoplasmic reticulum- derived transport vesicles. Required for efficient transport of a subset of secretory proteins to the Golgi. Facilitates retrograde transport from the Golgi to the endoplasmic reticulum (By similarity) | acyl-coA desaturase (predicted); Utilizes O(2) and electrons from the reduced cytochrome b(5) domain to catalyze the insertion of a double bond into a spectrum of fatty acyl-CoA substrates (By similarity) | 0.744 |
| erv25 | sec11 | SPAC23H4.03c.1 | SPBC1685.03.1 | COPII-coated vesicle component Erv25 (predicted); Constituent of COPII-coated endoplasmic reticulum- derived transport vesicles. Required for efficient transport of a subset of secretory proteins to the Golgi. Facilitates retrograde transport from the Golgi to the endoplasmic reticulum (By similarity) | signal peptidase subunit Sec11 (predicted); Catalytic component of the signal peptidase complex (SPC), which catalyzes the cleavage of N-terminal signal sequences of proteins targeted to the endoplasmic reticulum. Signal peptide cleavage occurs during the translocation (cotranslationally or post-translationally) through the translocon pore into the endoplasmic reticulum (By similarity) | 0.999 |
| erv25 | spc2 | SPAC23H4.03c.1 | SPAC1071.04c.1 | COPII-coated vesicle component Erv25 (predicted); Constituent of COPII-coated endoplasmic reticulum- derived transport vesicles. Required for efficient transport of a subset of secretory proteins to the Golgi. Facilitates retrograde transport from the Golgi to the endoplasmic reticulum (By similarity) | signal peptidase subunit Spc2 (predicted); Nonessential component of the signal peptidase complex (SPC), which catalyzes the cleavage of N-terminal signal sequences of proteins targeted to the endoplasmic reticulum. Signal peptide cleavage occurs during the translocation (cotranslationally or post-translationally) through the translocon pore into the endoplasmic reticulum. Spc2 enhances the enzymatic activity of SPC and facilitates the interactions between different components of the translocation site (By similarity) | 0.845 |
| lsm8 | spc2 | SPCC1840.10.1 | SPAC1071.04c.1 | U6 snRNP-associated protein Lsm8 (predicted); Probable component of the spliceosome | signal peptidase subunit Spc2 (predicted); Nonessential component of the signal peptidase complex (SPC), which catalyzes the cleavage of N-terminal signal sequences of proteins targeted to the endoplasmic reticulum. Signal peptide cleavage occurs during the translocation (cotranslationally or post-translationally) through the translocon pore into the endoplasmic reticulum. Spc2 enhances the enzymatic activity of SPC and facilitates the interactions between different components of the translocation site (By similarity) | 0.485 |
| ppn1 | spc2 | SPBC713.07c.1 | SPAC1071.04c.1 | vacuolar polyphosphatase (predicted); Catalyzes the hydrolysis of inorganic polyphosphate (poly P) chains of many hundreds of phosphate residues into shorter lengths (By similarity) | signal peptidase subunit Spc2 (predicted); Nonessential component of the signal peptidase complex (SPC), which catalyzes the cleavage of N-terminal signal sequences of proteins targeted to the endoplasmic reticulum. Signal peptide cleavage occurs during the translocation (cotranslationally or post-translationally) through the translocon pore into the endoplasmic reticulum. Spc2 enhances the enzymatic activity of SPC and facilitates the interactions between different components of the translocation site (By similarity) | 0.736 |
| sec11 | SPBC2D10.07c.1 | SPBC1685.03.1 | SPBC2D10.07c.1 | signal peptidase subunit Sec11 (predicted); Catalytic component of the signal peptidase complex (SPC), which catalyzes the cleavage of N-terminal signal sequences of proteins targeted to the endoplasmic reticulum. Signal peptide cleavage occurs during the translocation (cotranslationally or post-translationally) through the translocon pore into the endoplasmic reticulum (By similarity) | mitochondrial inner membrane peptidase complex catalytic subunit (predicted); Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space (By similarity) | 0.572 |
| sec11 | SPCC1281.06c.1 | SPBC1685.03.1 | SPCC1281.06c.1 | signal peptidase subunit Sec11 (predicted); Catalytic component of the signal peptidase complex (SPC), which catalyzes the cleavage of N-terminal signal sequences of proteins targeted to the endoplasmic reticulum. Signal peptide cleavage occurs during the translocation (cotranslationally or post-translationally) through the translocon pore into the endoplasmic reticulum (By similarity) | acyl-coA desaturase (predicted); Utilizes O(2) and electrons from the reduced cytochrome b(5) domain to catalyze the insertion of a double bond into a spectrum of fatty acyl-CoA substrates (By similarity) | 0.773 |
| sec11 | erv25 | SPBC1685.03.1 | SPAC23H4.03c.1 | signal peptidase subunit Sec11 (predicted); Catalytic component of the signal peptidase complex (SPC), which catalyzes the cleavage of N-terminal signal sequences of proteins targeted to the endoplasmic reticulum. Signal peptide cleavage occurs during the translocation (cotranslationally or post-translationally) through the translocon pore into the endoplasmic reticulum (By similarity) | COPII-coated vesicle component Erv25 (predicted); Constituent of COPII-coated endoplasmic reticulum- derived transport vesicles. Required for efficient transport of a subset of secretory proteins to the Golgi. Facilitates retrograde transport from the Golgi to the endoplasmic reticulum (By similarity) | 0.999 |
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