| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| kex1 | krp1 | SPBC16G5.09.1 | SPAC22E12.09c.1 | serine carboxypeptidase (predicted); Protease with a carboxypeptidase B-like function involved in the C-terminal processing of the lysine and arginine residues from protein precursors. Promotes cell fusion and is involved in the programmed cell death (By similarity) | kexin; Membrane-bound, subtilisin-like serine protease that processes the P-factor precursor and other precursor proteins. Essential for cell viability | 0.930 |
| kex1 | sxa1 | SPBC16G5.09.1 | SPAC26A3.01.1 | serine carboxypeptidase (predicted); Protease with a carboxypeptidase B-like function involved in the C-terminal processing of the lysine and arginine residues from protein precursors. Promotes cell fusion and is involved in the programmed cell death (By similarity) | aspartic protease Sxa1; Involved in degradation or processing of the mating pheromones. Its loss may cause a persistent response to the pheromones. It may cleave the mating pheromone M-factor. May be involved in processing of zymogens that are required for zygote formation | 0.418 |
| kex1 | vps1302 | SPBC16G5.09.1 | SPBC16C6.02c.1 | serine carboxypeptidase (predicted); Protease with a carboxypeptidase B-like function involved in the C-terminal processing of the lysine and arginine residues from protein precursors. Promotes cell fusion and is involved in the programmed cell death (By similarity) | chorein homolog (predicted); May be involved in recycling of membrane proteins between an endocytic compartment and the TGN (By similarity) | 0.571 |
| kex1 | vps13a | SPBC16G5.09.1 | SPBC21C3.01c.1 | serine carboxypeptidase (predicted); Protease with a carboxypeptidase B-like function involved in the C-terminal processing of the lysine and arginine residues from protein precursors. Promotes cell fusion and is involved in the programmed cell death (By similarity) | chorein homolog (predicted); May be involved in recycling of membrane proteins between an endocytic compartment and the TGN (By similarity) | 0.571 |
| kex1 | yps1 | SPBC16G5.09.1 | SPCC1795.09.1 | serine carboxypeptidase (predicted); Protease with a carboxypeptidase B-like function involved in the C-terminal processing of the lysine and arginine residues from protein precursors. Promotes cell fusion and is involved in the programmed cell death (By similarity) | aspartic protease, yapsin Yps1; Cleaves at paired basic residues | 0.418 |
| krp1 | kex1 | SPAC22E12.09c.1 | SPBC16G5.09.1 | kexin; Membrane-bound, subtilisin-like serine protease that processes the P-factor precursor and other precursor proteins. Essential for cell viability | serine carboxypeptidase (predicted); Protease with a carboxypeptidase B-like function involved in the C-terminal processing of the lysine and arginine residues from protein precursors. Promotes cell fusion and is involved in the programmed cell death (By similarity) | 0.930 |
| krp1 | psp3 | SPAC22E12.09c.1 | SPAC1006.01.1 | kexin; Membrane-bound, subtilisin-like serine protease that processes the P-factor precursor and other precursor proteins. Essential for cell viability | vacuolar serine protease Psp3 (predicted) | 0.911 |
| krp1 | sec71 | SPAC22E12.09c.1 | SPAC4D7.01c.1 | kexin; Membrane-bound, subtilisin-like serine protease that processes the P-factor precursor and other precursor proteins. Essential for cell viability | Sec7 domain protein, ARF GEF (predicted); May play a role in protein transport (By similarity) | 0.946 |
| krp1 | sec72 | SPAC22E12.09c.1 | SPAC30.01c.1 | kexin; Membrane-bound, subtilisin-like serine protease that processes the P-factor precursor and other precursor proteins. Essential for cell viability | Sec7 domain protein, ARF GEF Sec72; May play a role in protein transport (By similarity) | 0.946 |
| krp1 | spo2 | SPAC22E12.09c.1 | SPBC16C6.14.1 | kexin; Membrane-bound, subtilisin-like serine protease that processes the P-factor precursor and other precursor proteins. Essential for cell viability | sporulation specific protein Spo2; Involved in sporulation. Plays a significant role in modification of the spindle pole body prior to spore formation and is required for initiating forespore membrane formation. Assists in the localization of spo13 to the outer surface of the SPB | 0.948 |
| krp1 | spo20 | SPAC22E12.09c.1 | SPAC3H8.10.1 | kexin; Membrane-bound, subtilisin-like serine protease that processes the P-factor precursor and other precursor proteins. Essential for cell viability | sec14 cytosolic factor family Sec14; Required for transport of secretory proteins from the Golgi complex. Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes in vitro. Essential for viability and secretion | 0.914 |
| krp1 | sxa1 | SPAC22E12.09c.1 | SPAC26A3.01.1 | kexin; Membrane-bound, subtilisin-like serine protease that processes the P-factor precursor and other precursor proteins. Essential for cell viability | aspartic protease Sxa1; Involved in degradation or processing of the mating pheromones. Its loss may cause a persistent response to the pheromones. It may cleave the mating pheromone M-factor. May be involved in processing of zymogens that are required for zygote formation | 0.942 |
| krp1 | vps1302 | SPAC22E12.09c.1 | SPBC16C6.02c.1 | kexin; Membrane-bound, subtilisin-like serine protease that processes the P-factor precursor and other precursor proteins. Essential for cell viability | chorein homolog (predicted); May be involved in recycling of membrane proteins between an endocytic compartment and the TGN (By similarity) | 0.951 |
| krp1 | vps13a | SPAC22E12.09c.1 | SPBC21C3.01c.1 | kexin; Membrane-bound, subtilisin-like serine protease that processes the P-factor precursor and other precursor proteins. Essential for cell viability | chorein homolog (predicted); May be involved in recycling of membrane proteins between an endocytic compartment and the TGN (By similarity) | 0.951 |
| krp1 | yps1 | SPAC22E12.09c.1 | SPCC1795.09.1 | kexin; Membrane-bound, subtilisin-like serine protease that processes the P-factor precursor and other precursor proteins. Essential for cell viability | aspartic protease, yapsin Yps1; Cleaves at paired basic residues | 0.945 |
| psp3 | krp1 | SPAC1006.01.1 | SPAC22E12.09c.1 | vacuolar serine protease Psp3 (predicted) | kexin; Membrane-bound, subtilisin-like serine protease that processes the P-factor precursor and other precursor proteins. Essential for cell viability | 0.911 |
| psp3 | sxa1 | SPAC1006.01.1 | SPAC26A3.01.1 | vacuolar serine protease Psp3 (predicted) | aspartic protease Sxa1; Involved in degradation or processing of the mating pheromones. Its loss may cause a persistent response to the pheromones. It may cleave the mating pheromone M-factor. May be involved in processing of zymogens that are required for zygote formation | 0.685 |
| psp3 | yps1 | SPAC1006.01.1 | SPCC1795.09.1 | vacuolar serine protease Psp3 (predicted) | aspartic protease, yapsin Yps1; Cleaves at paired basic residues | 0.660 |
| sec71 | krp1 | SPAC4D7.01c.1 | SPAC22E12.09c.1 | Sec7 domain protein, ARF GEF (predicted); May play a role in protein transport (By similarity) | kexin; Membrane-bound, subtilisin-like serine protease that processes the P-factor precursor and other precursor proteins. Essential for cell viability | 0.946 |
| sec71 | spo20 | SPAC4D7.01c.1 | SPAC3H8.10.1 | Sec7 domain protein, ARF GEF (predicted); May play a role in protein transport (By similarity) | sec14 cytosolic factor family Sec14; Required for transport of secretory proteins from the Golgi complex. Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes in vitro. Essential for viability and secretion | 0.615 |
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