| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SPBC2D10.07c.1 | SPBC336.13c.1 | SPBC2D10.07c.1 | SPBC336.13c.1 | mitochondrial inner membrane peptidase complex catalytic subunit (predicted); Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space (By similarity) | mitochondrial inner membrane peptidase complex catalytic subunit 2 (predicted); Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space (By similarity) | 0.970 |
| SPBC2D10.07c.1 | dcr1 | SPBC2D10.07c.1 | SPCC188.13c.1 | mitochondrial inner membrane peptidase complex catalytic subunit (predicted); Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space (By similarity) | dicer; Required for G1 arrest and mating in response to nitrogen starvation. Ago1 regulation of cytokinesis and cell cycle checkpoints occurs downstream of dcr1. Required, indirectly, for regulated hyperphosphorylation of cdc2 | 0.841 |
| SPBC2D10.07c.1 | fas2 | SPBC2D10.07c.1 | SPAC4A8.11c.1 | mitochondrial inner membrane peptidase complex catalytic subunit (predicted); Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space (By similarity) | fatty acid synthase alpha subunit Lsd1; Fatty acid synthetase catalyzes the formation of long- chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. The alpha subunit contains domains for- acyl carrier protein, 3- oxoacyl-[acyl-carrier-protein] reductase, and 3-oxoacyl-[acyl- carrier-protein] synthase. This subunit coordinates the binding of the six beta subunits to the enzyme complex | 0.667 |
| SPBC2D10.07c.1 | glt1 | SPBC2D10.07c.1 | SPAPB1E7.07.1 | mitochondrial inner membrane peptidase complex catalytic subunit (predicted); Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space (By similarity) | glutamate synthase Glt1 (predicted); Forms L-glutamate from L-glutamine and 2-oxoglutarate. Represents an alternative pathway to L-glutamate dehydrogenase for the biosynthesis of L-glutamate. Participates with glutamine synthetase in ammonia assimilation processes. The enzyme is specific for NADH, L-glutamine and 2-oxoglutarate (By similarity) | 0.712 |
| SPBC2D10.07c.1 | grn1 | SPBC2D10.07c.1 | SPBC26H8.08c.1 | mitochondrial inner membrane peptidase complex catalytic subunit (predicted); Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space (By similarity) | GTPase Grn1; Required for optimal growth. Required for normal processing of ribosomal pre-rRNA. Required for nuclear export of ribosomal protein rpl2501 | 0.664 |
| SPBC2D10.07c.1 | guf1 | SPBC2D10.07c.1 | SPAC1B3.04c.1 | mitochondrial inner membrane peptidase complex catalytic subunit (predicted); Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space (By similarity) | mitochondrial GTPase involved in translation Guf1 (predicted); Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one- codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner (By similarity) | 0.735 |
| SPBC2D10.07c.1 | mrpl3 | SPBC2D10.07c.1 | SPBC3B9.14c.1 | mitochondrial inner membrane peptidase complex catalytic subunit (predicted); Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space (By similarity) | mitochondrial ribosomal protein subunit L3 (predicted) | 0.717 |
| SPBC2D10.07c.1 | mtg1 | SPBC2D10.07c.1 | SPBC25B2.04c.1 | mitochondrial inner membrane peptidase complex catalytic subunit (predicted); Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space (By similarity) | mitochondrial GTPase involved in translation Mtg1 (predicted); Mitochondrial GTPase involved in assembly of the large ribosomal subunit. Plays a role in expression of the mitochondrial translational machinery (By similarity) | 0.664 |
| SPBC2D10.07c.1 | pac1 | SPBC2D10.07c.1 | SPBC119.11c.1 | mitochondrial inner membrane peptidase complex catalytic subunit (predicted); Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space (By similarity) | double-strand-specific ribonuclease Pac1; Digests double-stranded RNA. Converts long double- stranded RNAs into short oligonucleotides, leaving 5’-phosphates on their cleavage products. Probably inhibits mating and meiosis by degrading a specific mRNA required for sexual development | 0.717 |
| SPBC2D10.07c.1 | rnh201 | SPBC2D10.07c.1 | SPAC4G9.02.1 | mitochondrial inner membrane peptidase complex catalytic subunit (predicted); Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space (By similarity) | ribonuclease H2 complex subunit Rnh201 (predicted); Endonuclease that specifically degrades the RNA of RNA- DNA hybrids. Participates in DNA replication | 0.702 |
| SPBC336.13c.1 | SPBC2D10.07c.1 | SPBC336.13c.1 | SPBC2D10.07c.1 | mitochondrial inner membrane peptidase complex catalytic subunit 2 (predicted); Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space (By similarity) | mitochondrial inner membrane peptidase complex catalytic subunit (predicted); Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space (By similarity) | 0.970 |
| SPBC336.13c.1 | dcr1 | SPBC336.13c.1 | SPCC188.13c.1 | mitochondrial inner membrane peptidase complex catalytic subunit 2 (predicted); Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space (By similarity) | dicer; Required for G1 arrest and mating in response to nitrogen starvation. Ago1 regulation of cytokinesis and cell cycle checkpoints occurs downstream of dcr1. Required, indirectly, for regulated hyperphosphorylation of cdc2 | 0.841 |
| SPBC336.13c.1 | fas2 | SPBC336.13c.1 | SPAC4A8.11c.1 | mitochondrial inner membrane peptidase complex catalytic subunit 2 (predicted); Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space (By similarity) | fatty acid synthase alpha subunit Lsd1; Fatty acid synthetase catalyzes the formation of long- chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. The alpha subunit contains domains for- acyl carrier protein, 3- oxoacyl-[acyl-carrier-protein] reductase, and 3-oxoacyl-[acyl- carrier-protein] synthase. This subunit coordinates the binding of the six beta subunits to the enzyme complex | 0.667 |
| SPBC336.13c.1 | glt1 | SPBC336.13c.1 | SPAPB1E7.07.1 | mitochondrial inner membrane peptidase complex catalytic subunit 2 (predicted); Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space (By similarity) | glutamate synthase Glt1 (predicted); Forms L-glutamate from L-glutamine and 2-oxoglutarate. Represents an alternative pathway to L-glutamate dehydrogenase for the biosynthesis of L-glutamate. Participates with glutamine synthetase in ammonia assimilation processes. The enzyme is specific for NADH, L-glutamine and 2-oxoglutarate (By similarity) | 0.712 |
| SPBC336.13c.1 | grn1 | SPBC336.13c.1 | SPBC26H8.08c.1 | mitochondrial inner membrane peptidase complex catalytic subunit 2 (predicted); Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space (By similarity) | GTPase Grn1; Required for optimal growth. Required for normal processing of ribosomal pre-rRNA. Required for nuclear export of ribosomal protein rpl2501 | 0.664 |
| SPBC336.13c.1 | guf1 | SPBC336.13c.1 | SPAC1B3.04c.1 | mitochondrial inner membrane peptidase complex catalytic subunit 2 (predicted); Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space (By similarity) | mitochondrial GTPase involved in translation Guf1 (predicted); Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one- codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner (By similarity) | 0.735 |
| SPBC336.13c.1 | mrpl3 | SPBC336.13c.1 | SPBC3B9.14c.1 | mitochondrial inner membrane peptidase complex catalytic subunit 2 (predicted); Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space (By similarity) | mitochondrial ribosomal protein subunit L3 (predicted) | 0.717 |
| SPBC336.13c.1 | mtg1 | SPBC336.13c.1 | SPBC25B2.04c.1 | mitochondrial inner membrane peptidase complex catalytic subunit 2 (predicted); Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space (By similarity) | mitochondrial GTPase involved in translation Mtg1 (predicted); Mitochondrial GTPase involved in assembly of the large ribosomal subunit. Plays a role in expression of the mitochondrial translational machinery (By similarity) | 0.664 |
| SPBC336.13c.1 | pac1 | SPBC336.13c.1 | SPBC119.11c.1 | mitochondrial inner membrane peptidase complex catalytic subunit 2 (predicted); Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space (By similarity) | double-strand-specific ribonuclease Pac1; Digests double-stranded RNA. Converts long double- stranded RNAs into short oligonucleotides, leaving 5’-phosphates on their cleavage products. Probably inhibits mating and meiosis by degrading a specific mRNA required for sexual development | 0.717 |
| SPBC336.13c.1 | rnh201 | SPBC336.13c.1 | SPAC4G9.02.1 | mitochondrial inner membrane peptidase complex catalytic subunit 2 (predicted); Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space (By similarity) | ribonuclease H2 complex subunit Rnh201 (predicted); Endonuclease that specifically degrades the RNA of RNA- DNA hybrids. Participates in DNA replication | 0.702 |
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