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ALDH1A3 ALDH1A3 ENSG00000257767 ENSG00000257767 ENSG00000269469 ENSG00000269469 ALDH2 ALDH2 TH TH PAH PAH AUH AUH ECHDC2 ECHDC2 HIBCH HIBCH ALDH3B2 ALDH3B2 EHHADH EHHADH HADHA HADHA ALDH7A1 ALDH7A1 ALDH1L1 ALDH1L1 CDY1 CDY1 ECI1 ECI1 IFFO2 IFFO2 ECHDC1 ECHDC1 ALDH8A1 ALDH8A1 HBZ HBZ HBB HBB HBQ1 HBQ1 HBA1 HBA1 HBA2 HBA2 AHSP AHSP HBE1 HBE1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
HBQ1hemoglobin, theta 1 (142 aa)
EHHADHenoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase (723 aa)
HBA2hemoglobin, alpha 2 (142 aa)
HBZhemoglobin, zeta; The zeta chain is an alpha-type chain of mammalian embryonic hemoglobin, synthesized primarily in the yolk sac (142 aa)
ALDH3B2aldehyde dehydrogenase 3 family, member B2 (385 aa)
ALDH2aldehyde dehydrogenase 2 family (mitochondrial) (517 aa)
ALDH8A1aldehyde dehydrogenase 8 family, member A1; Converts 9-cis-retinal to 9-cis-retinoic acid. Has lower activity towards 13-cis-retinal. Has much lower activity towards all-trans-retinal. Has highest activity with benzaldehyde and decanal (in vitro). Has a preference for NAD, but shows considerable activity with NADP (in vitro) (487 aa)
HBE1hemoglobin, epsilon 1; The epsilon chain is a beta-type chain of early mammalian embryonic hemoglobin (147 aa)
ECI1enoyl-CoA delta isomerase 1; Able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species (302 aa)
CDY1chromodomain protein, Y-linked, 1; Has histone acetyltransferase activity, with a preference for histone H4 (554 aa)
AHSPalpha hemoglobin stabilizing protein; Acts as a chaperone to prevent the harmful aggregation of alpha-hemoglobin during normal erythroid cell development. Specifically protects free alpha-hemoglobin from precipitation. It is predicted to modulate pathological states of alpha-hemoglobin excess such as beta-thalassemia (102 aa)
HBA1hemoglobin, alpha 1; Involved in oxygen transport from the lung to the various peripheral tissues (By similarity) (142 aa)
ALDH1A3aldehyde dehydrogenase 1 family, member A3; Recognizes as substrates free retinal and cellular retinol-binding protein-bound retinal. Seems to be the key enzyme in the formation of an RA gradient along the dorso-ventral axis during the early eye development and also in the development of the olfactory system (By similarity) (512 aa)
HBBhemoglobin, beta (147 aa)
HIBCH3-hydroxyisobutyryl-CoA hydrolase; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Also hydrolyzes 3-hydroxypropanoyl-CoA (386 aa)
ECHDC2enoyl CoA hydratase domain containing 2 (292 aa)
AUHAU RNA binding protein/enoyl-CoA hydratase; Catalyzes the conversion of 3-methylglutaconyl-CoA to 3- hydroxy-3-methylglutaryl-CoA. Has very low enoyl-CoA hydratase activity. Was originally identified as RNA-binding protein that binds in vitro to clustered 5’-AUUUA-3’ motifs (339 aa)
HADHAhydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit; Bifunctional subunit (763 aa)
THtyrosine hydroxylase; Plays an important role in the physiology of adrenergic neurons (528 aa)
ALDH1L1aldehyde dehydrogenase 1 family, member L1 (902 aa)
ALDH7A1aldehyde dehydrogenase 7 family, member A1; Multifunctional enzyme mediating important protective effects. Metabolizes betaine aldehyde to betaine, an important cellular osmolyte and methyl donor. Protects cells from oxidative stress by metabolizing a number of lipid peroxidation-derived aldehydes. Involved in lysine catabolism (539 aa)
IFFO2intermediate filament family orphan 2 (517 aa)
ECHDC1enoyl CoA hydratase domain containing 1 (307 aa)
PAHphenylalanine hydroxylase (452 aa)
ENSG00000257767Uncharacterized protein (245 aa)
ENSG00000269469Uncharacterized protein (72 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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