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MKRN2 | makorin ring finger protein 2; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins (By similarity) (416 aa) | |||
GSTT2 | glutathione S-transferase theta 2; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has a sulfatase activity (244 aa) | |||
RHBDD3 | rhomboid domain containing 3 (386 aa) | |||
GSTZ1 | glutathione S-transferase zeta 1 (216 aa) | |||
WASL | Wiskott-Aldrich syndrome-like; Regulates actin polymerization by stimulating the actin- nucleating activity of the Arp2/3 complex. Binds to HSF1/HSTF1 and forms a complex on heat shock promoter elements (HSE) that negatively regulates HSP90 expression (505 aa) | |||
OAS3 | 2’-5’-oligoadenylate synthetase 3, 100kDa; Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviral response. In addition, it may also play a role in other cellular processes such as apoptosis, cell growth, differentiation and gene regulation. Synthesizes preferentially dimers of 2’-5’- oligoadenylates (2-5A) from ATP which then bind to the inactive monomeric form of ribonuclease L (RNase L) leading to its dimerization and subsequent activation. Activation of RNase L leads to degradation of cellular as well as viral RNA, resulting in [...] (1087 aa) | |||
GSTT1 | glutathione S-transferase theta 1; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Acts on 1,2- epoxy-3-(4-nitrophenoxy)propane, phenethylisothiocyanate 4- nitrobenzyl chloride and 4-nitrophenethyl bromide. Displays glutathione peroxidase activity with cumene hydroperoxide (240 aa) | |||
SLC31A2 | solute carrier family 31 (copper transporters), member 2; Involved in low-affinity copper uptake (Potential) (143 aa) | |||
MARS | methionyl-tRNA synthetase (900 aa) | |||
ZC3H3 | zinc finger CCCH-type containing 3 (948 aa) | |||
GSTT2B | glutathione S-transferase theta 2B (gene/pseudogene); Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has a sulfatase activity (244 aa) | |||
CPSF4 | cleavage and polyadenylation specific factor 4, 30kDa; Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3’-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. CPSF4 binds RNA polymers with a preference for poly(U) (269 aa) | |||
EEF1G | eukaryotic translation elongation factor 1 gamma; Probably plays a role in anchoring the complex to other cellular components (437 aa) | |||
CPSF4L | cleavage and polyadenylation specific factor 4-like (179 aa) | |||
UBC | ubiquitin C (685 aa) | |||
SLC31A1 | solute carrier family 31 (copper transporters), member 1; High-affinity, saturable copper transporter involved in dietary copper uptake (190 aa) | |||
VARS | valyl-tRNA synthetase (1264 aa) | |||
TM9SF2 | transmembrane 9 superfamily member 2; In the intracellular compartments, may function as a channel or small molecule transporter (663 aa) | |||
EEF1E1 | eukaryotic translation elongation factor 1 epsilon 1; Positive modulator of ATM response to DNA damage (174 aa) | |||
CTNS | cystinosin, lysosomal cystine transporter; Thought to transport cystine out of lysosomes (400 aa) | |||
AIMP3 | HCG2043275; Uncharacterized protein (151 aa) | |||
TM9SF4 | transmembrane 9 superfamily protein member 4 (642 aa) | |||
ZC3H8 | zinc finger CCCH-type containing 8; Acts as a transcriptional repressor of the GATA3 promoter. Sequence-specific DNA-binding factor that binds to the 5’-AGGTCTC-3’ sequence within the negative cis-acting element intronic regulatory region (IRR) of the GATA3 gene (By similarity). Induces thymocyte apoptosis when overexpressed, which may indicate a role in regulation of thymocyte homeostasis (291 aa) | |||
ZC3H6 | zinc finger CCCH-type containing 6 (1189 aa) | |||
ENSG00000232856 | hsa-mir-3654 (206 aa) |