node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
COL13A1 | COL1A1 | ENSP00000381949 | ENSP00000225964 | collagen, type XIII, alpha 1 | collagen, type I, alpha 1 | 0.907 |
COL13A1 | COL4A1 | ENSP00000381949 | ENSP00000364979 | collagen, type XIII, alpha 1 | collagen, type IV, alpha 1; Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a ’chicken-wire’ meshwork together with laminins, proteoglycans and entactin/nidogen | 0.903 |
COL13A1 | HSPG2 | ENSP00000381949 | ENSP00000363827 | collagen, type XIII, alpha 1 | heparan sulfate proteoglycan 2; Integral component of basement membranes. Component of the glomerular basement membrane (GBM), responsible for the fixed negative electrostatic membrane charge, and which provides a barrier which is both size- and charge-selective. It serves as an attachment substrate for cells. Plays essential roles in vascularization. Critical for normal heart development and for regulating the vascular response to injury. Also required for avascular cartilage development | 0.599 |
COL13A1 | NID1 | ENSP00000381949 | ENSP00000264187 | collagen, type XIII, alpha 1 | nidogen 1; Sulfated glycoprotein widely distributed in basement membranes and tightly associated with laminin. Also binds to collagen IV and perlecan. It probably has a role in cell- extracellular matrix interactions | 0.566 |
COL13A1 | NID2 | ENSP00000381949 | ENSP00000216286 | collagen, type XIII, alpha 1 | nidogen 2 (osteonidogen); Cell adhesion glycoprotein which is widely distributed in basement membranes. Binds to collagens I and IV, to perlecan and to laminin 1. Does not bind fibulins. It probably has a role in cell-extracellular matrix interactions | 0.604 |
COL1A1 | COL13A1 | ENSP00000225964 | ENSP00000381949 | collagen, type I, alpha 1 | collagen, type XIII, alpha 1 | 0.907 |
COL1A1 | COL4A1 | ENSP00000225964 | ENSP00000364979 | collagen, type I, alpha 1 | collagen, type IV, alpha 1; Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a ’chicken-wire’ meshwork together with laminins, proteoglycans and entactin/nidogen | 0.928 |
COL1A1 | FBLN1 | ENSP00000225964 | ENSP00000331544 | collagen, type I, alpha 1 | fibulin 1 | 0.405 |
COL1A1 | HSPG2 | ENSP00000225964 | ENSP00000363827 | collagen, type I, alpha 1 | heparan sulfate proteoglycan 2; Integral component of basement membranes. Component of the glomerular basement membrane (GBM), responsible for the fixed negative electrostatic membrane charge, and which provides a barrier which is both size- and charge-selective. It serves as an attachment substrate for cells. Plays essential roles in vascularization. Critical for normal heart development and for regulating the vascular response to injury. Also required for avascular cartilage development | 0.608 |
COL1A1 | NID1 | ENSP00000225964 | ENSP00000264187 | collagen, type I, alpha 1 | nidogen 1; Sulfated glycoprotein widely distributed in basement membranes and tightly associated with laminin. Also binds to collagen IV and perlecan. It probably has a role in cell- extracellular matrix interactions | 0.872 |
COL1A1 | NID2 | ENSP00000225964 | ENSP00000216286 | collagen, type I, alpha 1 | nidogen 2 (osteonidogen); Cell adhesion glycoprotein which is widely distributed in basement membranes. Binds to collagens I and IV, to perlecan and to laminin 1. Does not bind fibulins. It probably has a role in cell-extracellular matrix interactions | 0.651 |
COL1A1 | PRELP | ENSP00000225964 | ENSP00000343924 | collagen, type I, alpha 1 | proline/arginine-rich end leucine-rich repeat protein; May anchor basement membranes to the underlying connective tissue (By similarity) | 0.592 |
COL4A1 | COL13A1 | ENSP00000364979 | ENSP00000381949 | collagen, type IV, alpha 1; Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a ’chicken-wire’ meshwork together with laminins, proteoglycans and entactin/nidogen | collagen, type XIII, alpha 1 | 0.903 |
COL4A1 | COL1A1 | ENSP00000364979 | ENSP00000225964 | collagen, type IV, alpha 1; Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a ’chicken-wire’ meshwork together with laminins, proteoglycans and entactin/nidogen | collagen, type I, alpha 1 | 0.928 |
COL4A1 | FBLN1 | ENSP00000364979 | ENSP00000331544 | collagen, type IV, alpha 1; Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a ’chicken-wire’ meshwork together with laminins, proteoglycans and entactin/nidogen | fibulin 1 | 0.407 |
COL4A1 | FBLN2 | ENSP00000364979 | ENSP00000384169 | collagen, type IV, alpha 1; Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a ’chicken-wire’ meshwork together with laminins, proteoglycans and entactin/nidogen | fibulin 2; Its binding to fibronectin and some other ligands is calcium dependent | 0.705 |
COL4A1 | HSPG2 | ENSP00000364979 | ENSP00000363827 | collagen, type IV, alpha 1; Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a ’chicken-wire’ meshwork together with laminins, proteoglycans and entactin/nidogen | heparan sulfate proteoglycan 2; Integral component of basement membranes. Component of the glomerular basement membrane (GBM), responsible for the fixed negative electrostatic membrane charge, and which provides a barrier which is both size- and charge-selective. It serves as an attachment substrate for cells. Plays essential roles in vascularization. Critical for normal heart development and for regulating the vascular response to injury. Also required for avascular cartilage development | 0.748 |
COL4A1 | LAMC1 | ENSP00000364979 | ENSP00000258341 | collagen, type IV, alpha 1; Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a ’chicken-wire’ meshwork together with laminins, proteoglycans and entactin/nidogen | laminin, gamma 1 (formerly LAMB2); Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components | 0.448 |
COL4A1 | NID1 | ENSP00000364979 | ENSP00000264187 | collagen, type IV, alpha 1; Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a ’chicken-wire’ meshwork together with laminins, proteoglycans and entactin/nidogen | nidogen 1; Sulfated glycoprotein widely distributed in basement membranes and tightly associated with laminin. Also binds to collagen IV and perlecan. It probably has a role in cell- extracellular matrix interactions | 0.967 |
COL4A1 | NID2 | ENSP00000364979 | ENSP00000216286 | collagen, type IV, alpha 1; Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a ’chicken-wire’ meshwork together with laminins, proteoglycans and entactin/nidogen | nidogen 2 (osteonidogen); Cell adhesion glycoprotein which is widely distributed in basement membranes. Binds to collagens I and IV, to perlecan and to laminin 1. Does not bind fibulins. It probably has a role in cell-extracellular matrix interactions | 0.857 |