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STRINGSTRING
RPL10L RPL10L RPL7A RPL7A RPL36A RPL36A RPL12 RPL12 RPL36AL RPL36AL RPL17 RPL17 RPL3 RPL3 RPL26 RPL26 RPL31 RPL31 RPL27A RPL27A RPL18A RPL18A RPL26L1 RPL26L1 RPLP2 RPLP2 RPL9 RPL9 RPL11 RPL11 RPL34 RPL34 RPL10A RPL10A RPS26 RPS26 EIF5 EIF5 RPS11 RPS11 RPS12 RPS12 RPS25 RPS25 EIF3H EIF3H EIF3G EIF3G EIF4A1 EIF4A1 EIF1 EIF1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
EIF5eukaryotic translation initiation factor 5; Catalyzes the hydrolysis of GTP bound to the 40S ribosomal initiation complex (40S.mRNA.Met-tRNA[F].eIF-2.GTP) with the subsequent joining of a 60S ribosomal subunit resulting in the release of eIF-2 and the guanine nucleotide. The subsequent joining of a 60S ribosomal subunit results in the formation of a functional 80S initiation complex (80S.mRNA.Met-tRNA[F]) (431 aa)
RPL18Aribosomal protein L18a (176 aa)
RPS12ribosomal protein S12 (132 aa)
EIF3Geukaryotic translation initiation factor 3, subunit G; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2-GTP-methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination riboso [...] (320 aa)
RPL26L1ribosomal protein L26-like 1 (145 aa)
RPS11ribosomal protein S11 (158 aa)
EIF4A1eukaryotic translation initiation factor 4A1; ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5’-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (406 aa)
RPL26ribosomal protein L26 (145 aa)
RPL10Lribosomal protein L10-like; May play a role in compensating for the inactivated X- linked gene during spermatogenesis (214 aa)
RPLP2ribosomal protein, large, P2; Plays an important role in the elongation step of protein synthesis (115 aa)
RPL3ribosomal protein L3; The L3 protein is a component of the large subunit of cytoplasmic ribosomes (403 aa)
RPL36ALribosomal protein L36a-like (106 aa)
RPL27Aribosomal protein L27a (148 aa)
RPL9ribosomal protein L9 (192 aa)
RPS26ribosomal protein S26 (115 aa)
RPL12ribosomal protein L12; Binds directly to 26S ribosomal RNA (By similarity) (165 aa)
RPL7Aribosomal protein L7a (266 aa)
RPL10Aribosomal protein L10a (217 aa)
RPL11ribosomal protein L11; Binds to 5S ribosomal RNA (By similarity). Required for rRNA maturation and formation of the 60S ribosomal subunits. Promotes nucleolar location of PML (By similarity) (178 aa)
RPL34ribosomal protein L34 (117 aa)
RPL31ribosomal protein L31 (128 aa)
RPL36Aribosomal protein L36a (142 aa)
EIF1eukaryotic translation initiation factor 1; Necessary for scanning and involved in initiation site selection. Promotes the assembly of 48S ribosomal complexes at the authentic initiation codon of a conventional capped mRNA (113 aa)
EIF3Heukaryotic translation initiation factor 3, subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2-GTP-methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination riboso [...] (352 aa)
RPS25ribosomal protein S25 (125 aa)
RPL17ribosomal protein L17 (184 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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