node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ARL6IP1 | RTN4 | ENSP00000306788 | ENSP00000337838 | ADP-ribosylation factor-like 6 interacting protein 1; May be involved in protein transport, membrane trafficking, or cell signaling during hematopoietic maturation | reticulon 4 | 0.777 |
ARL6IP1 | UBC | ENSP00000306788 | ENSP00000344818 | ADP-ribosylation factor-like 6 interacting protein 1; May be involved in protein transport, membrane trafficking, or cell signaling during hematopoietic maturation | ubiquitin C | 0.970 |
KRTAP10-5 | KRTAP5-9 | ENSP00000383223 | ENSP00000431443 | keratin associated protein 10-5; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins | keratin associated protein 5-9; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated protein (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins | 0.606 |
KRTAP5-9 | KRTAP10-5 | ENSP00000431443 | ENSP00000383223 | keratin associated protein 5-9; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated protein (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins | keratin associated protein 10-5; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins | 0.606 |
RABAC1 | UBC | ENSP00000222008 | ENSP00000344818 | Rab acceptor 1 (prenylated); General Rab protein regulator required for vesicle formation from the Golgi complex. May control vesicle docking and fusion by mediating the action of Rab GTPases to the SNARE complexes. In addition it inhibits the removal of Rab GTPases from the membrane by GDI (By similarity) | ubiquitin C | 0.963 |
REEP6 | RTN4 | ENSP00000233596 | ENSP00000337838 | receptor accessory protein 6; May enhance the cell surface expression of odorant receptors (By similarity) | reticulon 4 | 0.461 |
REEP6 | UBC | ENSP00000233596 | ENSP00000344818 | receptor accessory protein 6; May enhance the cell surface expression of odorant receptors (By similarity) | ubiquitin C | 0.486 |
RTN4 | ARL6IP1 | ENSP00000337838 | ENSP00000306788 | reticulon 4 | ADP-ribosylation factor-like 6 interacting protein 1; May be involved in protein transport, membrane trafficking, or cell signaling during hematopoietic maturation | 0.777 |
RTN4 | REEP6 | ENSP00000337838 | ENSP00000233596 | reticulon 4 | receptor accessory protein 6; May enhance the cell surface expression of odorant receptors (By similarity) | 0.461 |
RTN4 | UBC | ENSP00000337838 | ENSP00000344818 | reticulon 4 | ubiquitin C | 0.902 |
RTN4 | ZFYVE21 | ENSP00000337838 | ENSP00000216602 | reticulon 4 | zinc finger, FYVE domain containing 21; Plays a role in cell adhesion, and thereby in cell motility, regulating microtubule-induced PTK2/FAK1 dephosphorylation, an event important for focal adhesion disassemblya, as well as integrin beta-1/ITGB1 cell surface expression | 0.549 |
TYMS | UBC | ENSP00000315644 | ENSP00000344818 | thymidylate synthetase; Contributes to the de novo mitochondrial thymidylate biosynthesis pathway | ubiquitin C | 0.967 |
TYMS | ZFYVE21 | ENSP00000315644 | ENSP00000216602 | thymidylate synthetase; Contributes to the de novo mitochondrial thymidylate biosynthesis pathway | zinc finger, FYVE domain containing 21; Plays a role in cell adhesion, and thereby in cell motility, regulating microtubule-induced PTK2/FAK1 dephosphorylation, an event important for focal adhesion disassemblya, as well as integrin beta-1/ITGB1 cell surface expression | 0.644 |
UBC | ARL6IP1 | ENSP00000344818 | ENSP00000306788 | ubiquitin C | ADP-ribosylation factor-like 6 interacting protein 1; May be involved in protein transport, membrane trafficking, or cell signaling during hematopoietic maturation | 0.970 |
UBC | RABAC1 | ENSP00000344818 | ENSP00000222008 | ubiquitin C | Rab acceptor 1 (prenylated); General Rab protein regulator required for vesicle formation from the Golgi complex. May control vesicle docking and fusion by mediating the action of Rab GTPases to the SNARE complexes. In addition it inhibits the removal of Rab GTPases from the membrane by GDI (By similarity) | 0.963 |
UBC | REEP6 | ENSP00000344818 | ENSP00000233596 | ubiquitin C | receptor accessory protein 6; May enhance the cell surface expression of odorant receptors (By similarity) | 0.486 |
UBC | RTN4 | ENSP00000344818 | ENSP00000337838 | ubiquitin C | reticulon 4 | 0.902 |
UBC | TYMS | ENSP00000344818 | ENSP00000315644 | ubiquitin C | thymidylate synthetase; Contributes to the de novo mitochondrial thymidylate biosynthesis pathway | 0.967 |
UBC | VAT1 | ENSP00000344818 | ENSP00000347872 | ubiquitin C | vesicle amine transport protein 1 homolog (T. californica); Possesses ATPase activity (By similarity). Plays a part in calcium-regulated keratinocyte activation in epidermal repair mechanisms. Has no effect on cell proliferation. Negatively regulates mitochondrial fusion in cooperation with mitofusin proteins (MFN1-2) | 0.931 |
VAT1 | UBC | ENSP00000347872 | ENSP00000344818 | vesicle amine transport protein 1 homolog (T. californica); Possesses ATPase activity (By similarity). Plays a part in calcium-regulated keratinocyte activation in epidermal repair mechanisms. Has no effect on cell proliferation. Negatively regulates mitochondrial fusion in cooperation with mitofusin proteins (MFN1-2) | ubiquitin C | 0.931 |