| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AR | PPARG | ENSP00000363822 | ENSP00000287820 | androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins. Transcription activation is down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3 | peroxisome proliferator-activated receptor gamma | 0.920 |
| PPARG | AR | ENSP00000287820 | ENSP00000363822 | peroxisome proliferator-activated receptor gamma | androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins. Transcription activation is down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3 | 0.920 |
| PPARG | UCP1 | ENSP00000287820 | ENSP00000262999 | peroxisome proliferator-activated receptor gamma | uncoupling protein 1 (mitochondrial, proton carrier); UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat | 0.949 |
| PPARG | UCP2 | ENSP00000287820 | ENSP00000312029 | peroxisome proliferator-activated receptor gamma | uncoupling protein 2 (mitochondrial, proton carrier); UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat | 0.946 |
| PPARG | UCP3 | ENSP00000287820 | ENSP00000323740 | peroxisome proliferator-activated receptor gamma | uncoupling protein 3 (mitochondrial, proton carrier); UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation. As a result, energy is dissipated in the form of heat. May play a role in the modulation of tissue respiratory control. Participates in thermogenesis and energy balance | 0.942 |
| UCP1 | PPARG | ENSP00000262999 | ENSP00000287820 | uncoupling protein 1 (mitochondrial, proton carrier); UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat | peroxisome proliferator-activated receptor gamma | 0.949 |
| UCP1 | UCP2 | ENSP00000262999 | ENSP00000312029 | uncoupling protein 1 (mitochondrial, proton carrier); UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat | uncoupling protein 2 (mitochondrial, proton carrier); UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat | 0.903 |
| UCP1 | UCP3 | ENSP00000262999 | ENSP00000323740 | uncoupling protein 1 (mitochondrial, proton carrier); UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat | uncoupling protein 3 (mitochondrial, proton carrier); UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation. As a result, energy is dissipated in the form of heat. May play a role in the modulation of tissue respiratory control. Participates in thermogenesis and energy balance | 0.903 |
| UCP2 | PPARG | ENSP00000312029 | ENSP00000287820 | uncoupling protein 2 (mitochondrial, proton carrier); UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat | peroxisome proliferator-activated receptor gamma | 0.946 |
| UCP2 | UCP1 | ENSP00000312029 | ENSP00000262999 | uncoupling protein 2 (mitochondrial, proton carrier); UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat | uncoupling protein 1 (mitochondrial, proton carrier); UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat | 0.903 |
| UCP2 | UCP3 | ENSP00000312029 | ENSP00000323740 | uncoupling protein 2 (mitochondrial, proton carrier); UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat | uncoupling protein 3 (mitochondrial, proton carrier); UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation. As a result, energy is dissipated in the form of heat. May play a role in the modulation of tissue respiratory control. Participates in thermogenesis and energy balance | 0.901 |
| UCP3 | PPARG | ENSP00000323740 | ENSP00000287820 | uncoupling protein 3 (mitochondrial, proton carrier); UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation. As a result, energy is dissipated in the form of heat. May play a role in the modulation of tissue respiratory control. Participates in thermogenesis and energy balance | peroxisome proliferator-activated receptor gamma | 0.942 |
| UCP3 | UCP1 | ENSP00000323740 | ENSP00000262999 | uncoupling protein 3 (mitochondrial, proton carrier); UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation. As a result, energy is dissipated in the form of heat. May play a role in the modulation of tissue respiratory control. Participates in thermogenesis and energy balance | uncoupling protein 1 (mitochondrial, proton carrier); UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat | 0.903 |
| UCP3 | UCP2 | ENSP00000323740 | ENSP00000312029 | uncoupling protein 3 (mitochondrial, proton carrier); UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation. As a result, energy is dissipated in the form of heat. May play a role in the modulation of tissue respiratory control. Participates in thermogenesis and energy balance | uncoupling protein 2 (mitochondrial, proton carrier); UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat | 0.901 |
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