adenylate cyclase 2 (brain); This is a membrane-bound, calmodulin-insensitive adenylyl cyclase

adenylate cyclase 3; Mediates odorant detection (possibly) via modulation of intracellular cAMP concentration

adenylate cyclase 2 (brain); This is a membrane-bound, calmodulin-insensitive adenylyl cyclase

adenylate cyclase 9; May play a fundamental role in situations where fine interplay between intracellular calcium and cAMP determines the cellular function. May be a physiologically relevant docking site for calcineurin (By similarity)

adenylate cyclase 2 (brain); This is a membrane-bound, calmodulin-insensitive adenylyl cyclase

adenosine A1 receptor; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase

adenylate cyclase 2 (brain); This is a membrane-bound, calmodulin-insensitive adenylyl cyclase

complement component 5; Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex. C5b has a transient binding site for C6. The C5b-C6 complex is the foundation upon which the lytic complex is assembled

adenylate cyclase 2 (brain); This is a membrane-bound, calmodulin-insensitive adenylyl cyclase

chemokine (C-C motif) receptor 4; High affinity receptor for the C-C type chemokines CCL17/TARC and CCL22/MDC. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol- calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival

adenylate cyclase 2 (brain); This is a membrane-bound, calmodulin-insensitive adenylyl cyclase

chemokine (C-C motif) receptor 6; Receptor for a C-C type chemokine. Binds to MIP-3- alpha/LARC and subsequently transduces a signal by increasing the intracellular calcium ions level

adenylate cyclase 2 (brain); This is a membrane-bound, calmodulin-insensitive adenylyl cyclase

guanine nucleotide binding protein (G protein), beta polypeptide 4; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction

adenylate cyclase 2 (brain); This is a membrane-bound, calmodulin-insensitive adenylyl cyclase

guanine nucleotide binding protein (G protein), beta 5; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction

adenylate cyclase 2 (brain); This is a membrane-bound, calmodulin-insensitive adenylyl cyclase

guanine nucleotide binding protein (G protein), gamma 11; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction (By similarity)

adenylate cyclase 2 (brain); This is a membrane-bound, calmodulin-insensitive adenylyl cyclase

guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction (By similarity)

adenylate cyclase 2 (brain); This is a membrane-bound, calmodulin-insensitive adenylyl cyclase

5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled; This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins

adenylate cyclase 2 (brain); This is a membrane-bound, calmodulin-insensitive adenylyl cyclase

kininogen 1; (1) Kininogens are inhibitors of thiol proteases; (2) HMW-kininogen plays an important role in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII; (3) HMW-kininogen inhibits the thrombin- and plasmin- induced aggregation of thrombocytes; (4) the active peptide bradykinin that is released from HMW-kininogen shows a variety of physiological effects- (4A) influence in smooth muscle contraction, (4B) induction of hypotension, (4C) natriuresis and diuresis, (4D) decrease in blood glucose level, (4E) it is a mediator of inflammation [...]

adenylate cyclase 2 (brain); This is a membrane-bound, calmodulin-insensitive adenylyl cyclase

lysophosphatidic acid receptor 2; Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Seems to be coupled to the G(i)/G(o), G(12)/G(13), and G(q) families of heteromeric G proteins. Plays a key role in phospholipase C-beta (PLC-beta) signaling pathway. Stimulates phospholipase C (PLC) activity in a manner that is independent of RALA activation

adenylate cyclase 2 (brain); This is a membrane-bound, calmodulin-insensitive adenylyl cyclase

lysophosphatidic acid receptor 5; Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities

adenylate cyclase 2 (brain); This is a membrane-bound, calmodulin-insensitive adenylyl cyclase

melanin-concentrating hormone receptor 1; Receptor for melanin-concentrating hormone, coupled to both G proteins that inhibit adenylyl cyclase and G proteins that activate phosphoinositide hydrolysis

adenylate cyclase 2 (brain); This is a membrane-bound, calmodulin-insensitive adenylyl cyclase

sphingosine-1-phosphate receptor 4; Receptor for the lysosphingolipid sphingosine 1- phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. May be involved in cell migration processes that are specific for lymphocytes

adenylate cyclase 2 (brain); This is a membrane-bound, calmodulin-insensitive adenylyl cyclase

sphingosine-1-phosphate receptor 5; Receptor for the lysosphingolipid sphingosine 1- phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. Is coupled to both the G(i/0)alpha and G(12) subclass of heteromeric G-proteins (By similarity). May play a regulatory role in the transformation of radial glial cells into astrocytes and may affect proliferative activity of these cells

adenylate cyclase 2 (brain); This is a membrane-bound, calmodulin-insensitive adenylyl cyclase

somatostatin; Somatostatin inhibits the release of somatotropin

adenylate cyclase 2 (brain); This is a membrane-bound, calmodulin-insensitive adenylyl cyclase

taste receptor, type 2, member 40; Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5

adenylate cyclase 2 (brain); This is a membrane-bound, calmodulin-insensitive adenylyl cyclase

taste receptor, type 2, member 43; Gustducin-coupled receptor immplicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5. Activated by the sulfonyl amide sweeteners saccharin and acesulfame K. In airway epithelial cells, binding of bitter compounds increases the intracellular calcium ion concentration and stimulates ciliary beat frequency. May act as chemosensory receptors in airway epithelial cells to detect and eliminate potential noxious agents from the airways (By similarity)