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TMEM30A | transmembrane protein 30A (361 aa) | |||
PEMT | phosphatidylethanolamine N-methyltransferase (236 aa) | |||
PIKFYVE | phosphoinositide kinase, FYVE finger containing; The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Catalyzes the phosphorylation of phosphatidylinositol 3-phosphate on the fifth hydroxyl of the myo- inositol ring, to form phosphatidylinositol 3,5-bisphosphate. Required for endocytic-vacuolar pathway and nuclear migration. Plays a role in the biogenesis of endosome carrier vesicles (ECV)/ multivesicular bodies (MVB) transport intermediates from early endosomes (2098 aa) | |||
ATP10D | ATPase, class V, type 10D (1426 aa) | |||
RAB41 | RAB41, member RAS oncogene family (221 aa) | |||
ATP11A | ATPase, class VI, type 11A (1134 aa) | |||
ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1; May play a role in the transport of aminophospholipids from the outer to the inner leaflet of various membranes and the maintenance of asymmetric distribution of phospholipids in the canicular membrane. May have a role in transport of bile acids into the canaliculus, uptake of bile acids from intestinal contents into intestinal mucosa or both (1251 aa) | |||
ATP8B4 | ATPase, class I, type 8B, member 4 (1192 aa) | |||
RAB6B | RAB6B, member RAS oncogene family; Seems to have a role in retrograde membrane traffic at the level of the Golgi complex. May function in retrograde transport in neuronal cells (208 aa) | |||
GCN1L1 | GCN1 general control of amino-acid synthesis 1-like 1 (yeast) (2671 aa) | |||
UBB | ubiquitin B (229 aa) | |||
RAB6A | RAB6A, member RAS oncogene family; Protein transport. Regulator of membrane traffic from the Golgi apparatus towards the endoplasmic reticulum (ER). Has a low GTPase activity (208 aa) | |||
ATP10B | ATPase, class V, type 10B (1461 aa) | |||
ARFGAP1 | ADP-ribosylation factor GTPase activating protein 1 (414 aa) | |||
CNOT1 | CCR4-NOT transcription complex, subunit 1 (2376 aa) | |||
ATP11B | ATPase, class VI, type 11B (1177 aa) | |||
ATP11C | ATPase, class VI, type 11C (1132 aa) | |||
UBE2G2 | ubiquitin-conjugating enzyme E2G 2; Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes ’Lys- 48’-linked polyubiquitination. Involved in endoplasmic reticulum- associated degradation (ERAD) (165 aa) | |||
UBC | ubiquitin C (685 aa) | |||
ATP10A | ATPase, class V, type 10A (1499 aa) | |||
ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 (1223 aa) | |||
DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3; Involved in the unfolded protein response (UPR) during ER stress. Co-chaperone of HSPA8/HSC70, it stimulates its ATPase activity. May inhibit both the autophosphorylation of EIF2AK2/PKR and the ability of EIF2AK2 to catalyze phosphorylation of the EIF2A. May inhibit EIF2AK3/PERK activity (504 aa) | |||
ATP8A2 | ATPase, aminophospholipid transporter, class I, type 8A, member 2 (1188 aa) | |||
ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1; May play a role in the transport of aminophospholipids from the outer to the inner leaflet of various membranes and the maintenance of asymmetric distribution of phospholipids, mainly in secretory vesicles (1164 aa) | |||
ELAVL1 | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R); Involved in 3’-UTR ARE-mediated MYC stabilization. Binds avidly to the AU-rich element in FOS and IL3/interleukin-3 mRNAs. In the case of the FOS AU-rich element, HUR binds to a core element of 27 nucleotides that contain AUUUA, AUUUUA and AUUUUUA motifs. Binds preferentially to the 5’-UUUU[AG]UUU-3’ motif in vitro (326 aa) | |||
RAB6C | RAB6C, member RAS oncogene family; May be involved in the regulation of centrosome duplication and cell cycle progression (254 aa) |