node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CCNA1 | CCNB2 | ENSP00000255465 | ENSP00000288207 | cyclin A1; May be involved in the control of the cell cycle at the G1/S (start) and G2/M (mitosis) transitions. May primarily function in the control of the germline meiotic cell cycle and additionally in the control of mitotic cell cycle in some somatic cells | cyclin B2; Essential for the control of the cell cycle at the G2/M (mitosis) transition | 0.971 |
CCNA1 | CCNE1 | ENSP00000255465 | ENSP00000262643 | cyclin A1; May be involved in the control of the cell cycle at the G1/S (start) and G2/M (mitosis) transitions. May primarily function in the control of the germline meiotic cell cycle and additionally in the control of mitotic cell cycle in some somatic cells | cyclin E1; Essential for the control of the cell cycle at the G1/S (start) transition | 0.959 |
CCNA1 | CCNE2 | ENSP00000255465 | ENSP00000309181 | cyclin A1; May be involved in the control of the cell cycle at the G1/S (start) and G2/M (mitosis) transitions. May primarily function in the control of the germline meiotic cell cycle and additionally in the control of mitotic cell cycle in some somatic cells | cyclin E2; Essential for the control of the cell cycle at the late G1 and early S phase | 0.600 |
CCNA1 | CCNG1 | ENSP00000255465 | ENSP00000344635 | cyclin A1; May be involved in the control of the cell cycle at the G1/S (start) and G2/M (mitosis) transitions. May primarily function in the control of the germline meiotic cell cycle and additionally in the control of mitotic cell cycle in some somatic cells | cyclin G1; May play a role in growth regulation. Is associated with G2/M phase arrest in response to DNA damage. May be an intermediate by which p53 mediates its role as an inhibitor of cellular proliferation (By similarity) | 0.604 |
CCNA1 | CCNG2 | ENSP00000255465 | ENSP00000315743 | cyclin A1; May be involved in the control of the cell cycle at the G1/S (start) and G2/M (mitosis) transitions. May primarily function in the control of the germline meiotic cell cycle and additionally in the control of mitotic cell cycle in some somatic cells | cyclin G2; May play a role in growth regulation and in negative regulation of cell cycle progession | 0.609 |
CCNA2 | CCNB2 | ENSP00000274026 | ENSP00000288207 | cyclin A2; Essential for the control of the cell cycle at the G1/S (start) and the G2/M (mitosis) transitions | cyclin B2; Essential for the control of the cell cycle at the G2/M (mitosis) transition | 0.972 |
CCNA2 | CCNE1 | ENSP00000274026 | ENSP00000262643 | cyclin A2; Essential for the control of the cell cycle at the G1/S (start) and the G2/M (mitosis) transitions | cyclin E1; Essential for the control of the cell cycle at the G1/S (start) transition | 0.960 |
CCNA2 | CCNE2 | ENSP00000274026 | ENSP00000309181 | cyclin A2; Essential for the control of the cell cycle at the G1/S (start) and the G2/M (mitosis) transitions | cyclin E2; Essential for the control of the cell cycle at the late G1 and early S phase | 0.618 |
CCNA2 | CCNG1 | ENSP00000274026 | ENSP00000344635 | cyclin A2; Essential for the control of the cell cycle at the G1/S (start) and the G2/M (mitosis) transitions | cyclin G1; May play a role in growth regulation. Is associated with G2/M phase arrest in response to DNA damage. May be an intermediate by which p53 mediates its role as an inhibitor of cellular proliferation (By similarity) | 0.609 |
CCNA2 | CCNG2 | ENSP00000274026 | ENSP00000315743 | cyclin A2; Essential for the control of the cell cycle at the G1/S (start) and the G2/M (mitosis) transitions | cyclin G2; May play a role in growth regulation and in negative regulation of cell cycle progession | 0.619 |
CCNB2 | CCNA1 | ENSP00000288207 | ENSP00000255465 | cyclin B2; Essential for the control of the cell cycle at the G2/M (mitosis) transition | cyclin A1; May be involved in the control of the cell cycle at the G1/S (start) and G2/M (mitosis) transitions. May primarily function in the control of the germline meiotic cell cycle and additionally in the control of mitotic cell cycle in some somatic cells | 0.971 |
CCNB2 | CCNA2 | ENSP00000288207 | ENSP00000274026 | cyclin B2; Essential for the control of the cell cycle at the G2/M (mitosis) transition | cyclin A2; Essential for the control of the cell cycle at the G1/S (start) and the G2/M (mitosis) transitions | 0.972 |
CCNB2 | CCNE1 | ENSP00000288207 | ENSP00000262643 | cyclin B2; Essential for the control of the cell cycle at the G2/M (mitosis) transition | cyclin E1; Essential for the control of the cell cycle at the G1/S (start) transition | 0.496 |
CCNB2 | CCNE2 | ENSP00000288207 | ENSP00000309181 | cyclin B2; Essential for the control of the cell cycle at the G2/M (mitosis) transition | cyclin E2; Essential for the control of the cell cycle at the late G1 and early S phase | 0.495 |
CCNB2 | CCNF | ENSP00000288207 | ENSP00000380256 | cyclin B2; Essential for the control of the cell cycle at the G2/M (mitosis) transition | cyclin F; Substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of CP110 during G2 phase, thereby acting as an inhibitor of centrosome reduplication | 0.614 |
CCNB2 | CCNG1 | ENSP00000288207 | ENSP00000344635 | cyclin B2; Essential for the control of the cell cycle at the G2/M (mitosis) transition | cyclin G1; May play a role in growth regulation. Is associated with G2/M phase arrest in response to DNA damage. May be an intermediate by which p53 mediates its role as an inhibitor of cellular proliferation (By similarity) | 0.438 |
CCNB2 | PPP2CA | ENSP00000288207 | ENSP00000418447 | cyclin B2; Essential for the control of the cell cycle at the G2/M (mitosis) transition | protein phosphatase 2, catalytic subunit, alpha isozyme; PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGOL2 to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I (By similarity). Can dephosphorylate SV40 large T antigen and p53/TP53. Activates RAF1 by dephosphorylating it at ’Ser-259’ | 0.716 |
CCNE1 | CCNA1 | ENSP00000262643 | ENSP00000255465 | cyclin E1; Essential for the control of the cell cycle at the G1/S (start) transition | cyclin A1; May be involved in the control of the cell cycle at the G1/S (start) and G2/M (mitosis) transitions. May primarily function in the control of the germline meiotic cell cycle and additionally in the control of mitotic cell cycle in some somatic cells | 0.959 |
CCNE1 | CCNA2 | ENSP00000262643 | ENSP00000274026 | cyclin E1; Essential for the control of the cell cycle at the G1/S (start) transition | cyclin A2; Essential for the control of the cell cycle at the G1/S (start) and the G2/M (mitosis) transitions | 0.960 |
CCNE1 | CCNB2 | ENSP00000262643 | ENSP00000288207 | cyclin E1; Essential for the control of the cell cycle at the G1/S (start) transition | cyclin B2; Essential for the control of the cell cycle at the G2/M (mitosis) transition | 0.496 |