26 items (Homo sapiens) - STRING network view

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protein of unknown 3D structure

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	GTPBP1	GTP binding protein 1; Promotes degradation of target mRNA species. Plays a role in the regulation of circadian mRNA stability. Binds GTP and has GTPase activity (By similarity) (669 aa)
	GCDH	glutaryl-CoA dehydrogenase; Catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. Isoform Short is inactive (438 aa)
	SOGA1	suppressor of glucose, autophagy associated 1; Regulates autophagy by playing a role in the reduction of glucose production in an adiponectin- and insulin-dependent manner (By similarity) (1661 aa)
	ACADS	acyl-CoA dehydrogenase, C-2 to C-3 short chain (412 aa)
	NUMBL	numb homolog (Drosophila)-like; Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of embryonic neurogenesis. Also required postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. Negative regulator of NF-kappa-B signaling pathway. The inhibition of [...] (609 aa)
	PROX1	prospero homeobox 1; May play a fundamental role in early development of CNS. May regulate gene expression and development of postmitotic undifferentiated young neurons (By similarity) (737 aa)
	SAMHD1	SAM domain and HD domain 1; Putative nuclease involved in innate immune response by acting as a negative regulator of the cell-intrinsic antiviral response. May play a role in mediating proinflammatory responses to TNF-alpha signaling (626 aa)
	ACAD8	acyl-CoA dehydrogenase family, member 8; Has very high activity toward isobutyryl-CoA. Is an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Plays a role in transcriptional coactivation within the ARC complex (415 aa)
	FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) (1338 aa)
	ACOX1	acyl-CoA oxidase 1, palmitoyl (660 aa)
	ANKRA2	ankyrin repeat, family A (RFXANK-like), 2; May facilitate endocytosis by linking megalin to components of the cytoskeleton or endocytic machinery (313 aa)
	GTPBP2	GTP binding protein 2 (602 aa)
	RFXANK	regulatory factor X-associated ankyrin-containing protein; Activates transcription from class II MHC promoters. Activation requires the activity of the MHC class II transactivator (MHC2TA). May regulate other genes in the cell. RFX binds the X1 box of MHC-II promoters. Isoform RFX-B-delta5 is not involved in the positive regulation of MHC class II genes (260 aa)
	ACOX2	acyl-CoA oxidase 2, branched chain; Oxidizes the CoA esters of the bile acid intermediates di- and tri-hydroxycholestanoic acids (681 aa)
	ACAD9	acyl-CoA dehydrogenase family, member 9; Has a dehydrogenase activity on palmitoyl-CoA (C16-0) and stearoyl-CoA (C18-0). It is three times more active on palmitoyl-CoA than on stearoyl-CoA. Has little activity on octanoyl-CoA (C8-0), butyryl-CoA (C4-0) or isovaleryl-CoA (5-0) (621 aa)
	NUMB	numb homolog (Drosophila) (651 aa)
	ACOX3	acyl-CoA oxidase 3, pristanoyl; Oxidizes the CoA-esters of 2-methyl-branched fatty acids (By similarity) (700 aa)
	ACADVL	acyl-CoA dehydrogenase, very long chain; Active toward esters of long-chain and very long chain fatty acids such as palmitoyl-CoA, mysritoyl-CoA and stearoyl-CoA. Can accommodate substrate acyl chain lengths as long as 24 carbons, but shows little activity for substrates of less than 12 carbons (655 aa)
	ZNF219	zinc finger protein 219; May be involved in transcriptional regulation (722 aa)
	TSNAX	translin-associated factor X; Acts in combination with TSN as an endonuclease involved in the activation of the RNA-induced silencing complex (RISC). Possible role in spermatogenesis (290 aa)
	ACADSB	acyl-CoA dehydrogenase, short/branched chain; Has greatest activity toward short branched chain acyl- CoA derivative such as (s)-2-methylbutyryl-CoA, isobutyryl-CoA, and 2-methylhexanoyl-CoA as well as toward short straight chain acyl-CoAs such as butyryl-CoA and hexanoyl-CoA. Can use valproyl- CoA as substrate and may play a role in controlling the metabolic flux of valproic acid in the development of toxicity of this agent (432 aa)
	DTNA	dystrobrevin, alpha (743 aa)
	DTNB	dystrobrevin, beta (627 aa)
	MARK2	MAP/microtubule affinity-regulating kinase 2; Serine/threonine-protein kinase involved in cell polarity and microtubule dynamics regulation. Phosphorylates CRTC2/TORC2, DCX, HDAC7, KIF13B, MAP2, MAP4, MAPT/TAU, and RAB11FIP2. Plays a key role in cell polarity by phosphorylating the microtubule-associated proteins MAP2, MAP4 and MAPT/TAU at KXGS motifs, causing detachment from microtubules, and their disassembly. Regulates epithelial cell polarity by phosphorylating RAB11FIP2. Involved in the regulation of neuronal migration through its dual activities in regulating cellular polarity an [...] (788 aa)
	PROX2	prospero homeobox 2; Transcription regulator. Does not seem to be essential for embryonic development and postnatal survival (By similarity) (592 aa)
	ACOXL	acyl-CoA oxidase-like (580 aa)

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACADS	GCDH	ENSP00000242592	ENSP00000222214	acyl-CoA dehydrogenase, C-2 to C-3 short chain	glutaryl-CoA dehydrogenase; Catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. Isoform Short is inactive	0.923
ACADSB	GCDH	ENSP00000357873	ENSP00000222214	acyl-CoA dehydrogenase, short/branched chain; Has greatest activity toward short branched chain acyl- CoA derivative such as (s)-2-methylbutyryl-CoA, isobutyryl-CoA, and 2-methylhexanoyl-CoA as well as toward short straight chain acyl-CoAs such as butyryl-CoA and hexanoyl-CoA. Can use valproyl- CoA as substrate and may play a role in controlling the metabolic flux of valproic acid in the development of toxicity of this agent	glutaryl-CoA dehydrogenase; Catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. Isoform Short is inactive	0.924
ACADVL	ACOX1	ENSP00000349297	ENSP00000293217	acyl-CoA dehydrogenase, very long chain; Active toward esters of long-chain and very long chain fatty acids such as palmitoyl-CoA, mysritoyl-CoA and stearoyl-CoA. Can accommodate substrate acyl chain lengths as long as 24 carbons, but shows little activity for substrates of less than 12 carbons	acyl-CoA oxidase 1, palmitoyl	0.555
ACADVL	ACOX2	ENSP00000349297	ENSP00000307697	acyl-CoA dehydrogenase, very long chain; Active toward esters of long-chain and very long chain fatty acids such as palmitoyl-CoA, mysritoyl-CoA and stearoyl-CoA. Can accommodate substrate acyl chain lengths as long as 24 carbons, but shows little activity for substrates of less than 12 carbons	acyl-CoA oxidase 2, branched chain; Oxidizes the CoA esters of the bile acid intermediates di- and tri-hydroxycholestanoic acids	0.489
ACOX1	ACADVL	ENSP00000293217	ENSP00000349297	acyl-CoA oxidase 1, palmitoyl	acyl-CoA dehydrogenase, very long chain; Active toward esters of long-chain and very long chain fatty acids such as palmitoyl-CoA, mysritoyl-CoA and stearoyl-CoA. Can accommodate substrate acyl chain lengths as long as 24 carbons, but shows little activity for substrates of less than 12 carbons	0.555
ACOX1	GCDH	ENSP00000293217	ENSP00000222214	acyl-CoA oxidase 1, palmitoyl	glutaryl-CoA dehydrogenase; Catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. Isoform Short is inactive	0.951
ACOX2	ACADVL	ENSP00000307697	ENSP00000349297	acyl-CoA oxidase 2, branched chain; Oxidizes the CoA esters of the bile acid intermediates di- and tri-hydroxycholestanoic acids	acyl-CoA dehydrogenase, very long chain; Active toward esters of long-chain and very long chain fatty acids such as palmitoyl-CoA, mysritoyl-CoA and stearoyl-CoA. Can accommodate substrate acyl chain lengths as long as 24 carbons, but shows little activity for substrates of less than 12 carbons	0.489
ACOX2	GCDH	ENSP00000307697	ENSP00000222214	acyl-CoA oxidase 2, branched chain; Oxidizes the CoA esters of the bile acid intermediates di- and tri-hydroxycholestanoic acids	glutaryl-CoA dehydrogenase; Catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. Isoform Short is inactive	0.534
ACOX3	GCDH	ENSP00000348775	ENSP00000222214	acyl-CoA oxidase 3, pristanoyl; Oxidizes the CoA-esters of 2-methyl-branched fatty acids (By similarity)	glutaryl-CoA dehydrogenase; Catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. Isoform Short is inactive	0.946
DTNA	GTPBP1	ENSP00000382064	ENSP00000216044	dystrobrevin, alpha	GTP binding protein 1; Promotes degradation of target mRNA species. Plays a role in the regulation of circadian mRNA stability. Binds GTP and has GTPase activity (By similarity)	0.573
DTNA	GTPBP2	ENSP00000382064	ENSP00000303997	dystrobrevin, alpha	GTP binding protein 2	0.573
DTNA	MARK2	ENSP00000382064	ENSP00000385751	dystrobrevin, alpha	MAP/microtubule affinity-regulating kinase 2; Serine/threonine-protein kinase involved in cell polarity and microtubule dynamics regulation. Phosphorylates CRTC2/TORC2, DCX, HDAC7, KIF13B, MAP2, MAP4, MAPT/TAU, and RAB11FIP2. Plays a key role in cell polarity by phosphorylating the microtubule-associated proteins MAP2, MAP4 and MAPT/TAU at KXGS motifs, causing detachment from microtubules, and their disassembly. Regulates epithelial cell polarity by phosphorylating RAB11FIP2. Involved in the regulation of neuronal migration through its dual activities in regulating cellular polarity an [...]	0.740
DTNA	SOGA1	ENSP00000382064	ENSP00000237536	dystrobrevin, alpha	suppressor of glucose, autophagy associated 1; Regulates autophagy by playing a role in the reduction of glucose production in an adiponectin- and insulin-dependent manner (By similarity)	0.634
DTNB	GTPBP1	ENSP00000384084	ENSP00000216044	dystrobrevin, beta	GTP binding protein 1; Promotes degradation of target mRNA species. Plays a role in the regulation of circadian mRNA stability. Binds GTP and has GTPase activity (By similarity)	0.573
DTNB	GTPBP2	ENSP00000384084	ENSP00000303997	dystrobrevin, beta	GTP binding protein 2	0.573
DTNB	SOGA1	ENSP00000384084	ENSP00000237536	dystrobrevin, beta	suppressor of glucose, autophagy associated 1; Regulates autophagy by playing a role in the reduction of glucose production in an adiponectin- and insulin-dependent manner (By similarity)	0.634
FLT1	SOGA1	ENSP00000282397	ENSP00000237536	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	suppressor of glucose, autophagy associated 1; Regulates autophagy by playing a role in the reduction of glucose production in an adiponectin- and insulin-dependent manner (By similarity)	0.576
GCDH	ACADS	ENSP00000222214	ENSP00000242592	glutaryl-CoA dehydrogenase; Catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. Isoform Short is inactive	acyl-CoA dehydrogenase, C-2 to C-3 short chain	0.923
GCDH	ACADSB	ENSP00000222214	ENSP00000357873	glutaryl-CoA dehydrogenase; Catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. Isoform Short is inactive	acyl-CoA dehydrogenase, short/branched chain; Has greatest activity toward short branched chain acyl- CoA derivative such as (s)-2-methylbutyryl-CoA, isobutyryl-CoA, and 2-methylhexanoyl-CoA as well as toward short straight chain acyl-CoAs such as butyryl-CoA and hexanoyl-CoA. Can use valproyl- CoA as substrate and may play a role in controlling the metabolic flux of valproic acid in the development of toxicity of this agent	0.924
GCDH	ACOX1	ENSP00000222214	ENSP00000293217	glutaryl-CoA dehydrogenase; Catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. Isoform Short is inactive	acyl-CoA oxidase 1, palmitoyl	0.951

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