node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CAD | CDS1 | ENSP00000264705 | ENSP00000295887 | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase) | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1; Provides CDP-diacylglycerol an important precursor for the synthesis of phosphatidylinositol (PtdIns), phosphatidylglycerol, and cardiolipin. Overexpression may amplify cellular signaling responses from cytokines. May also play an important role in the signal transduction mechanism of retina and neural cells | 0.487 |
CAD | CDS2 | ENSP00000264705 | ENSP00000419879 | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase) | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 | 0.492 |
CAD | CPS1 | ENSP00000264705 | ENSP00000402608 | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase) | carbamoyl-phosphate synthase 1, mitochondrial; Involved in the urea cycle of ureotelic animals where the enzyme plays an important role in removing excess ammonia from the cell | 0.999 |
CAD | CYB5R1 | ENSP00000264705 | ENSP00000356218 | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase) | cytochrome b5 reductase 1; NADH-cytochrome b5 reductases are involved in desaturation and elongation of fatty acids, cholesterol biosynthesis, drug metabolism, and, in erythrocyte, methemoglobin reduction (By similarity) | 0.851 |
CAD | CYB5R2 | ENSP00000264705 | ENSP00000299498 | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase) | cytochrome b5 reductase 2; NADH-cytochrome b5 reductases are involved in desaturation and elongation of fatty acids, cholesterol biosynthesis, drug metabolism, and, in erythrocyte, methemoglobin reduction (By similarity). Responsible for NADH-dependent lucigenin chemiluminescence in spermatozoa by reducing both lucigenin and 2-[4-iodophenyl]-3-[4-nitrophenyl]-5-[2,4- disulfophenyl]-2H tetrazolium monosodium salt (WST-1) | 0.849 |
CAD | CYB5R3 | ENSP00000264705 | ENSP00000354468 | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase) | cytochrome b5 reductase 3 | 0.849 |
CAD | SLC35C2 | ENSP00000264705 | ENSP00000243896 | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase) | solute carrier family 35, member C2; May play an important role in the cellular response to tissue hypoxia | 0.495 |
CAD | UBC | ENSP00000264705 | ENSP00000344818 | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase) | ubiquitin C | 0.874 |
CDS1 | CAD | ENSP00000295887 | ENSP00000264705 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1; Provides CDP-diacylglycerol an important precursor for the synthesis of phosphatidylinositol (PtdIns), phosphatidylglycerol, and cardiolipin. Overexpression may amplify cellular signaling responses from cytokines. May also play an important role in the signal transduction mechanism of retina and neural cells | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase) | 0.487 |
CDS1 | UBC | ENSP00000295887 | ENSP00000344818 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1; Provides CDP-diacylglycerol an important precursor for the synthesis of phosphatidylinositol (PtdIns), phosphatidylglycerol, and cardiolipin. Overexpression may amplify cellular signaling responses from cytokines. May also play an important role in the signal transduction mechanism of retina and neural cells | ubiquitin C | 0.547 |
CDS2 | CAD | ENSP00000419879 | ENSP00000264705 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase) | 0.492 |
CDS2 | UBC | ENSP00000419879 | ENSP00000344818 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 | ubiquitin C | 0.547 |
CPS1 | CAD | ENSP00000402608 | ENSP00000264705 | carbamoyl-phosphate synthase 1, mitochondrial; Involved in the urea cycle of ureotelic animals where the enzyme plays an important role in removing excess ammonia from the cell | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase) | 0.999 |
CPS1 | CYB5R1 | ENSP00000402608 | ENSP00000356218 | carbamoyl-phosphate synthase 1, mitochondrial; Involved in the urea cycle of ureotelic animals where the enzyme plays an important role in removing excess ammonia from the cell | cytochrome b5 reductase 1; NADH-cytochrome b5 reductases are involved in desaturation and elongation of fatty acids, cholesterol biosynthesis, drug metabolism, and, in erythrocyte, methemoglobin reduction (By similarity) | 0.823 |
CPS1 | CYB5R2 | ENSP00000402608 | ENSP00000299498 | carbamoyl-phosphate synthase 1, mitochondrial; Involved in the urea cycle of ureotelic animals where the enzyme plays an important role in removing excess ammonia from the cell | cytochrome b5 reductase 2; NADH-cytochrome b5 reductases are involved in desaturation and elongation of fatty acids, cholesterol biosynthesis, drug metabolism, and, in erythrocyte, methemoglobin reduction (By similarity). Responsible for NADH-dependent lucigenin chemiluminescence in spermatozoa by reducing both lucigenin and 2-[4-iodophenyl]-3-[4-nitrophenyl]-5-[2,4- disulfophenyl]-2H tetrazolium monosodium salt (WST-1) | 0.823 |
CPS1 | CYB5R3 | ENSP00000402608 | ENSP00000354468 | carbamoyl-phosphate synthase 1, mitochondrial; Involved in the urea cycle of ureotelic animals where the enzyme plays an important role in removing excess ammonia from the cell | cytochrome b5 reductase 3 | 0.823 |
CPS1 | UBC | ENSP00000402608 | ENSP00000344818 | carbamoyl-phosphate synthase 1, mitochondrial; Involved in the urea cycle of ureotelic animals where the enzyme plays an important role in removing excess ammonia from the cell | ubiquitin C | 0.962 |
CYB5R1 | CAD | ENSP00000356218 | ENSP00000264705 | cytochrome b5 reductase 1; NADH-cytochrome b5 reductases are involved in desaturation and elongation of fatty acids, cholesterol biosynthesis, drug metabolism, and, in erythrocyte, methemoglobin reduction (By similarity) | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase) | 0.851 |
CYB5R1 | CPS1 | ENSP00000356218 | ENSP00000402608 | cytochrome b5 reductase 1; NADH-cytochrome b5 reductases are involved in desaturation and elongation of fatty acids, cholesterol biosynthesis, drug metabolism, and, in erythrocyte, methemoglobin reduction (By similarity) | carbamoyl-phosphate synthase 1, mitochondrial; Involved in the urea cycle of ureotelic animals where the enzyme plays an important role in removing excess ammonia from the cell | 0.823 |
CYB5R1 | UBC | ENSP00000356218 | ENSP00000344818 | cytochrome b5 reductase 1; NADH-cytochrome b5 reductases are involved in desaturation and elongation of fatty acids, cholesterol biosynthesis, drug metabolism, and, in erythrocyte, methemoglobin reduction (By similarity) | ubiquitin C | 0.932 |