7 items (Homo sapiens) - STRING network view

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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Your Input:
	PSPN	persephin; Exhibits neurotrophic activity on mesencephalic dopaminergic and motor neurons (156 aa)
	NRTN	neurturin; Supports the survival of sympathetic neurons in culture. May regulate the development and maintenance of the CNS. Might control the size of non-neuronal cell population such as haemopoietic cells (197 aa)
	GFRA4	GDNF family receptor alpha 4; Receptor for persephin. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor. May be important in C-cell development and, in the postnatal development of the adrenal medulla (299 aa)
	NCAM1	neural cell adhesion molecule 1 (848 aa)
	ARTN	artemin; Ligand for the GFR-alpha-3-RET receptor complex but can also activate the GFR-alpha-1-RET receptor complex. Supports the survival of sensory and sympathetic peripheral neurons in culture and also supports the survival of dopaminergic neurons of the ventral mid-brain. Strong attractant of gut hematopoietic cells thus promoting the formation Peyer’s patch-like structures, a major component of the gut-associated lymphoid tissue (228 aa)
	GFRA1	GDNF family receptor alpha 1; Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor (By similarity) (465 aa)
	GDNF	glial cell derived neurotrophic factor (228 aa)

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARTN	GDNF	ENSP00000387435	ENSP00000409007	artemin; Ligand for the GFR-alpha-3-RET receptor complex but can also activate the GFR-alpha-1-RET receptor complex. Supports the survival of sensory and sympathetic peripheral neurons in culture and also supports the survival of dopaminergic neurons of the ventral mid-brain. Strong attractant of gut hematopoietic cells thus promoting the formation Peyer’s patch-like structures, a major component of the gut-associated lymphoid tissue	glial cell derived neurotrophic factor	0.920
ARTN	GFRA1	ENSP00000387435	ENSP00000393725	artemin; Ligand for the GFR-alpha-3-RET receptor complex but can also activate the GFR-alpha-1-RET receptor complex. Supports the survival of sensory and sympathetic peripheral neurons in culture and also supports the survival of dopaminergic neurons of the ventral mid-brain. Strong attractant of gut hematopoietic cells thus promoting the formation Peyer’s patch-like structures, a major component of the gut-associated lymphoid tissue	GDNF family receptor alpha 1; Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor (By similarity)	0.966
ARTN	GFRA4	ENSP00000387435	ENSP00000313423	artemin; Ligand for the GFR-alpha-3-RET receptor complex but can also activate the GFR-alpha-1-RET receptor complex. Supports the survival of sensory and sympathetic peripheral neurons in culture and also supports the survival of dopaminergic neurons of the ventral mid-brain. Strong attractant of gut hematopoietic cells thus promoting the formation Peyer’s patch-like structures, a major component of the gut-associated lymphoid tissue	GDNF family receptor alpha 4; Receptor for persephin. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor. May be important in C-cell development and, in the postnatal development of the adrenal medulla	0.749
ARTN	NCAM1	ENSP00000387435	ENSP00000318472	artemin; Ligand for the GFR-alpha-3-RET receptor complex but can also activate the GFR-alpha-1-RET receptor complex. Supports the survival of sensory and sympathetic peripheral neurons in culture and also supports the survival of dopaminergic neurons of the ventral mid-brain. Strong attractant of gut hematopoietic cells thus promoting the formation Peyer’s patch-like structures, a major component of the gut-associated lymphoid tissue	neural cell adhesion molecule 1	0.900
ARTN	NRTN	ENSP00000387435	ENSP00000302648	artemin; Ligand for the GFR-alpha-3-RET receptor complex but can also activate the GFR-alpha-1-RET receptor complex. Supports the survival of sensory and sympathetic peripheral neurons in culture and also supports the survival of dopaminergic neurons of the ventral mid-brain. Strong attractant of gut hematopoietic cells thus promoting the formation Peyer’s patch-like structures, a major component of the gut-associated lymphoid tissue	neurturin; Supports the survival of sympathetic neurons in culture. May regulate the development and maintenance of the CNS. Might control the size of non-neuronal cell population such as haemopoietic cells	0.921
ARTN	PSPN	ENSP00000387435	ENSP00000245810	artemin; Ligand for the GFR-alpha-3-RET receptor complex but can also activate the GFR-alpha-1-RET receptor complex. Supports the survival of sensory and sympathetic peripheral neurons in culture and also supports the survival of dopaminergic neurons of the ventral mid-brain. Strong attractant of gut hematopoietic cells thus promoting the formation Peyer’s patch-like structures, a major component of the gut-associated lymphoid tissue	persephin; Exhibits neurotrophic activity on mesencephalic dopaminergic and motor neurons	0.915
GDNF	ARTN	ENSP00000409007	ENSP00000387435	glial cell derived neurotrophic factor	artemin; Ligand for the GFR-alpha-3-RET receptor complex but can also activate the GFR-alpha-1-RET receptor complex. Supports the survival of sensory and sympathetic peripheral neurons in culture and also supports the survival of dopaminergic neurons of the ventral mid-brain. Strong attractant of gut hematopoietic cells thus promoting the formation Peyer’s patch-like structures, a major component of the gut-associated lymphoid tissue	0.920
GDNF	GFRA1	ENSP00000409007	ENSP00000393725	glial cell derived neurotrophic factor	GDNF family receptor alpha 1; Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor (By similarity)	0.999
GDNF	GFRA4	ENSP00000409007	ENSP00000313423	glial cell derived neurotrophic factor	GDNF family receptor alpha 4; Receptor for persephin. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor. May be important in C-cell development and, in the postnatal development of the adrenal medulla	0.512
GDNF	NCAM1	ENSP00000409007	ENSP00000318472	glial cell derived neurotrophic factor	neural cell adhesion molecule 1	0.916
GDNF	NRTN	ENSP00000409007	ENSP00000302648	glial cell derived neurotrophic factor	neurturin; Supports the survival of sympathetic neurons in culture. May regulate the development and maintenance of the CNS. Might control the size of non-neuronal cell population such as haemopoietic cells	0.919
GDNF	PSPN	ENSP00000409007	ENSP00000245810	glial cell derived neurotrophic factor	persephin; Exhibits neurotrophic activity on mesencephalic dopaminergic and motor neurons	0.916
GFRA1	ARTN	ENSP00000393725	ENSP00000387435	GDNF family receptor alpha 1; Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor (By similarity)	artemin; Ligand for the GFR-alpha-3-RET receptor complex but can also activate the GFR-alpha-1-RET receptor complex. Supports the survival of sensory and sympathetic peripheral neurons in culture and also supports the survival of dopaminergic neurons of the ventral mid-brain. Strong attractant of gut hematopoietic cells thus promoting the formation Peyer’s patch-like structures, a major component of the gut-associated lymphoid tissue	0.966
GFRA1	GDNF	ENSP00000393725	ENSP00000409007	GDNF family receptor alpha 1; Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor (By similarity)	glial cell derived neurotrophic factor	0.999
GFRA1	NCAM1	ENSP00000393725	ENSP00000318472	GDNF family receptor alpha 1; Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor (By similarity)	neural cell adhesion molecule 1	0.917
GFRA1	NRTN	ENSP00000393725	ENSP00000302648	GDNF family receptor alpha 1; Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor (By similarity)	neurturin; Supports the survival of sympathetic neurons in culture. May regulate the development and maintenance of the CNS. Might control the size of non-neuronal cell population such as haemopoietic cells	0.995
GFRA1	PSPN	ENSP00000393725	ENSP00000245810	GDNF family receptor alpha 1; Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor (By similarity)	persephin; Exhibits neurotrophic activity on mesencephalic dopaminergic and motor neurons	0.969
GFRA4	ARTN	ENSP00000313423	ENSP00000387435	GDNF family receptor alpha 4; Receptor for persephin. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor. May be important in C-cell development and, in the postnatal development of the adrenal medulla	artemin; Ligand for the GFR-alpha-3-RET receptor complex but can also activate the GFR-alpha-1-RET receptor complex. Supports the survival of sensory and sympathetic peripheral neurons in culture and also supports the survival of dopaminergic neurons of the ventral mid-brain. Strong attractant of gut hematopoietic cells thus promoting the formation Peyer’s patch-like structures, a major component of the gut-associated lymphoid tissue	0.749
GFRA4	GDNF	ENSP00000313423	ENSP00000409007	GDNF family receptor alpha 4; Receptor for persephin. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor. May be important in C-cell development and, in the postnatal development of the adrenal medulla	glial cell derived neurotrophic factor	0.512
GFRA4	NRTN	ENSP00000313423	ENSP00000302648	GDNF family receptor alpha 4; Receptor for persephin. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor. May be important in C-cell development and, in the postnatal development of the adrenal medulla	neurturin; Supports the survival of sympathetic neurons in culture. May regulate the development and maintenance of the CNS. Might control the size of non-neuronal cell population such as haemopoietic cells	0.623

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