26 items (Homo sapiens) - STRING network view

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	GNG13	guanine nucleotide binding protein (G protein), gamma 13; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction (67 aa)
	GNG11	guanine nucleotide binding protein (G protein), gamma 11; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction (By similarity) (73 aa)
	ADCY7	adenylate cyclase 7; This is a membrane-bound, calcium-inhibitable adenylyl cyclase (1080 aa)
	ADCY3	adenylate cyclase 3; Mediates odorant detection (possibly) via modulation of intracellular cAMP concentration (1144 aa)
	PRKCG	protein kinase C, gamma; Calcium-activated, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that plays diverse roles in neuronal cells and eye tissues, such as regulation of the neuronal receptors GRIA4/GLUR4 and GRIN1/NMDAR1, modulation of receptors and neuronal functions related to sensitivity to opiates, pain and alcohol, mediation of synaptic function and cell survival after ischemia, and inhibition of gap junction activity after oxidative stress. Binds and phosphorylates GRIA4/GLUR4 glutamate receptor and regulates its function by increasing plasma [...] (697 aa)
	ADCY8	adenylate cyclase 8 (brain); This is a membrane-bound, calcium-stimulable adenylyl cyclase. May be involved in learning, in memory and in drug dependence (By similarity) (1251 aa)
	KCNJ6	potassium inwardly-rectifying channel, subfamily J, member 6; This potassium channel may be involved in the regulation of insulin secretion by glucose and/or neurotransmitters acting through G-protein-coupled receptors. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly du [...] (423 aa)
	ADCY9	adenylate cyclase 9; May play a fundamental role in situations where fine interplay between intracellular calcium and cAMP determines the cellular function. May be a physiologically relevant docking site for calcineurin (By similarity) (1353 aa)
	GNG3	guanine nucleotide binding protein (G protein), gamma 3; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction (75 aa)
	ADCY1	adenylate cyclase 1 (brain); This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning (1119 aa)
	GNG8	guanine nucleotide binding protein (G protein), gamma 8; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction (70 aa)
	ADCY6	adenylate cyclase 6; Membrane-bound, calcium-inhibitable adenylyl cyclase (By similarity) (1168 aa)
	ADCY4	adenylate cyclase 4; This is a membrane-bound, calmodulin-insensitive adenylyl cyclase (By similarity) (1077 aa)
	GNG2	guanine nucleotide binding protein (G protein), gamma 2; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction (By similarity) (71 aa)
	ADCY2	adenylate cyclase 2 (brain); This is a membrane-bound, calmodulin-insensitive adenylyl cyclase (1091 aa)
	GNG4	guanine nucleotide binding protein (G protein), gamma 4; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction (By similarity) (75 aa)
	GNG5	guanine nucleotide binding protein (G protein), gamma 5; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction (68 aa)
	GNG12	guanine nucleotide binding protein (G protein), gamma 12; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction (By similarity) (72 aa)
	GNG10	guanine nucleotide binding protein (G protein), gamma 10; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. Interacts with beta-1 and beta-2, but not with beta-3 (68 aa)
	GNB1	guanine nucleotide binding protein (G protein), beta polypeptide 1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction (340 aa)
	GNG7	guanine nucleotide binding protein (G protein), gamma 7; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. Plays a role in the regulation of adenylyl cyclase signaling in certain regions of the brain. Plays a role in the formation or stabilzation of a G protein heterotrimer (G(olf) subunit alpha-beta-gamma-7) that is required for adenylyl cyclase activity in the striat [...] (68 aa)
	ADCYAP1R1	adenylate cyclase activating polypeptide 1 (pituitary) receptor type I; This is a receptor for PACAP-27 and PACAP-38. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. May regulate the release of adrenocorticotropin, luteinizing hormone, growth hormone, prolactin, epinephrine, and catecholamine. May play a role in spermatogenesis and sperm motility. Causes smooth muscle relaxation and secretion in the gastrointestinal tract (496 aa)
	GCGR	glucagon receptor; This is a receptor for glucagon which plays a central role in regulating the level of blood glucose by controlling the rate of hepatic glucose production and insulin secretion. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system (477 aa)
	GCG	glucagon; Glicentin may modulate gastric acid secretion and the gastro-pyloro-duodenal activity. May play an important role in intestinal mucosal growth in the early period of life (180 aa)
	PRKCA	protein kinase C, alpha; Calcium-activated, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that is involved in positive and negative regulation of cell proliferation, apoptosis, differentiation, migration and adhesion, tumorigenesis, cardiac hypertrophy, angiogenesis, platelet function and inflammation, by directly phosphorylating targets such as RAF1, BCL2, CSPG4, TNNT2/CTNT, or activating signaling cascade involving MAPK1/3 (ERK1/2) and RAP1GAP. Involved in cell proliferation and cell growth arrest by positive and negative regulation of the cell cycl [...] (672 aa)
	ADCY5	adenylate cyclase 5; This is a membrane-bound, calcium-inhibitable adenylyl cyclase (1261 aa)

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCY1	ADCY2	ENSP00000297323	ENSP00000342952	adenylate cyclase 1 (brain); This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning	adenylate cyclase 2 (brain); This is a membrane-bound, calmodulin-insensitive adenylyl cyclase	0.962
ADCY1	ADCY3	ENSP00000297323	ENSP00000260600	adenylate cyclase 1 (brain); This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning	adenylate cyclase 3; Mediates odorant detection (possibly) via modulation of intracellular cAMP concentration	0.911
ADCY1	ADCY4	ENSP00000297323	ENSP00000312126	adenylate cyclase 1 (brain); This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning	adenylate cyclase 4; This is a membrane-bound, calmodulin-insensitive adenylyl cyclase (By similarity)	0.915
ADCY1	ADCY5	ENSP00000297323	ENSP00000419361	adenylate cyclase 1 (brain); This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning	adenylate cyclase 5; This is a membrane-bound, calcium-inhibitable adenylyl cyclase	0.908
ADCY1	ADCY6	ENSP00000297323	ENSP00000311405	adenylate cyclase 1 (brain); This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning	adenylate cyclase 6; Membrane-bound, calcium-inhibitable adenylyl cyclase (By similarity)	0.907
ADCY1	ADCY7	ENSP00000297323	ENSP00000254235	adenylate cyclase 1 (brain); This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning	adenylate cyclase 7; This is a membrane-bound, calcium-inhibitable adenylyl cyclase	0.924
ADCY1	ADCY8	ENSP00000297323	ENSP00000286355	adenylate cyclase 1 (brain); This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning	adenylate cyclase 8 (brain); This is a membrane-bound, calcium-stimulable adenylyl cyclase. May be involved in learning, in memory and in drug dependence (By similarity)	0.910
ADCY1	ADCY9	ENSP00000297323	ENSP00000294016	adenylate cyclase 1 (brain); This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning	adenylate cyclase 9; May play a fundamental role in situations where fine interplay between intracellular calcium and cAMP determines the cellular function. May be a physiologically relevant docking site for calcineurin (By similarity)	0.928
ADCY1	ADCYAP1R1	ENSP00000297323	ENSP00000379514	adenylate cyclase 1 (brain); This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning	adenylate cyclase activating polypeptide 1 (pituitary) receptor type I; This is a receptor for PACAP-27 and PACAP-38. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. May regulate the release of adrenocorticotropin, luteinizing hormone, growth hormone, prolactin, epinephrine, and catecholamine. May play a role in spermatogenesis and sperm motility. Causes smooth muscle relaxation and secretion in the gastrointestinal tract	0.920
ADCY1	GCG	ENSP00000297323	ENSP00000387662	adenylate cyclase 1 (brain); This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning	glucagon; Glicentin may modulate gastric acid secretion and the gastro-pyloro-duodenal activity. May play an important role in intestinal mucosal growth in the early period of life	0.918
ADCY1	GCGR	ENSP00000297323	ENSP00000383558	adenylate cyclase 1 (brain); This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning	glucagon receptor; This is a receptor for glucagon which plays a central role in regulating the level of blood glucose by controlling the rate of hepatic glucose production and insulin secretion. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system	0.900
ADCY1	GNB1	ENSP00000297323	ENSP00000367869	adenylate cyclase 1 (brain); This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning	guanine nucleotide binding protein (G protein), beta polypeptide 1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction	0.950
ADCY1	GNG10	ENSP00000297323	ENSP00000363411	adenylate cyclase 1 (brain); This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning	guanine nucleotide binding protein (G protein), gamma 10; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. Interacts with beta-1 and beta-2, but not with beta-3	0.906
ADCY1	GNG11	ENSP00000297323	ENSP00000248564	adenylate cyclase 1 (brain); This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning	guanine nucleotide binding protein (G protein), gamma 11; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction (By similarity)	0.900
ADCY1	GNG12	ENSP00000297323	ENSP00000360021	adenylate cyclase 1 (brain); This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning	guanine nucleotide binding protein (G protein), gamma 12; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction (By similarity)	0.900
ADCY1	GNG13	ENSP00000297323	ENSP00000248150	adenylate cyclase 1 (brain); This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning	guanine nucleotide binding protein (G protein), gamma 13; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction	0.900
ADCY1	GNG2	ENSP00000297323	ENSP00000334448	adenylate cyclase 1 (brain); This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning	guanine nucleotide binding protein (G protein), gamma 2; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction (By similarity)	0.937
ADCY1	GNG3	ENSP00000297323	ENSP00000294117	adenylate cyclase 1 (brain); This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning	guanine nucleotide binding protein (G protein), gamma 3; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction	0.900
ADCY1	GNG4	ENSP00000297323	ENSP00000355556	adenylate cyclase 1 (brain); This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning	guanine nucleotide binding protein (G protein), gamma 4; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction (By similarity)	0.900
ADCY1	GNG5	ENSP00000297323	ENSP00000359675	adenylate cyclase 1 (brain); This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning	guanine nucleotide binding protein (G protein), gamma 5; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction	0.900

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